Protein Info for HSERO_RS15175 in Herbaspirillum seropedicae SmR1

Annotation: phosphoserine phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 TIGR00338: phosphoserine phosphatase SerB" amino acids 84 to 293 (210 residues), 226.8 bits, see alignment E=2.4e-71 PF00702: Hydrolase" amino acids 88 to 258 (171 residues), 71 bits, see alignment E=2.7e-23 TIGR01488: HAD phosphoserine phosphatase-like hydrolase, family IB" amino acids 89 to 258 (170 residues), 108.4 bits, see alignment E=4e-35 PF12710: HAD" amino acids 91 to 258 (168 residues), 71.8 bits, see alignment E=1.6e-23 PF08282: Hydrolase_3" amino acids 226 to 290 (65 residues), 30.2 bits, see alignment E=5.9e-11

Best Hits

KEGG orthology group: K01079, phosphoserine phosphatase [EC: 3.1.3.3] (inferred from 100% identity to hse:Hsero_3024)

Predicted SEED Role

"Phosphoserine phosphatase (EC 3.1.3.3)" in subsystem Glycine and Serine Utilization or Serine Biosynthesis (EC 3.1.3.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.3

Use Curated BLAST to search for 3.1.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8J0F6 at UniProt or InterPro

Protein Sequence (294 amino acids)

>HSERO_RS15175 phosphoserine phosphatase (Herbaspirillum seropedicae SmR1)
MNQQNNMNLILQAPKQHAVSSSAIEAIAALAGGDVERISDARVPDADVWRVAGVSLNEAL
KASVDAACLQARLDYAFIDADRKLADFRLVAMDMDSTLITIECIDEIADMQGLKPQVAEI
TEAAMRGEIEFNESLTRRVALLKGLDAGALQRVYDERLQLSPGAENMLKAVQAAGLKTLL
VSGGFTFFTDRMKARLNLDYTHANTLEVVDGKLTGKVVGGIVNADEKRATVERVCREIGA
EPTQAIVMGDGANDLRMMGISGLSVAFRAKPVVRAQASVGLNFVGLDGILNLLA