Protein Info for HSERO_RS12860 in Herbaspirillum seropedicae SmR1

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 592 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 180 to 200 (21 residues), see Phobius details PF05227: CHASE3" amino acids 44 to 172 (129 residues), 93.6 bits, see alignment E=2.6e-30 PF00989: PAS" amino acids 225 to 319 (95 residues), 25.3 bits, see alignment E=3.4e-09 TIGR00229: PAS domain S-box protein" amino acids 227 to 346 (120 residues), 52.7 bits, see alignment E=2.3e-18 PF13426: PAS_9" amino acids 233 to 338 (106 residues), 35.3 bits, see alignment E=3e-12 PF00512: HisKA" amino acids 368 to 434 (67 residues), 52.2 bits, see alignment E=1.3e-17 PF02518: HATPase_c" amino acids 477 to 584 (108 residues), 76.7 bits, see alignment E=5e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_2572)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-)" in subsystem Oxidative stress or Oxygen and light sensor PpaA-PpsR (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWQ1 at UniProt or InterPro

Protein Sequence (592 amino acids)

>HSERO_RS12860 histidine kinase (Herbaspirillum seropedicae SmR1)
MPITKQSQLARASTGIFFLLALLLSIGVAGFSYHSVRDFEQRAVWLQHTHTVINVLEETN
SALRETVGNSRGYVLSGNEEYRTSFEAGVRHVQALMQDLRRLMSDNERQIERLDSTEDLV
NQRLALSREILALRPEQARERVLEGKALSDEIRRRFAEMKGNENALLAKRSQDTSASADL
TIFMVVSGSLLSMALLVLVYSKLRREMDRRIDAQQRAQAYSDEIEDLYNNAPCGYHSVDE
SDKKIIKINDTELKWLGYTREQVVGRMTHTDLLAPASAERYLRELQPQFMLKREISGIDL
NYRRADGSEFTALVNATAIPSRDRSKLISRTVIYDISDRKRAEEEIEALNADLKRQALHL
HSVNKELESFSYSVSHDLRAPLRAISGYAMILEEDYADAIDEKGREQLQVIRRNVRKMDE
LINDLLKLAKSTTGELTLERFSMDDLVRQVIAGLRRENPNVLFDVPPLEGAVANRGLITQ
VWENLLSNAVKFSSKSEQPAVRVSMQVEPEEYIYGVHDNGVGFDMRYAHKLFGTFQRLHR
QEEYAGTGIGLALVQRIVIRHTGRVWAQSKPGEGASFYFSLPRKGLSPSLVE