Protein Info for HSERO_RS12450 in Herbaspirillum seropedicae SmR1

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1266 TIGR00229: PAS domain S-box protein" amino acids 427 to 549 (123 residues), 54 bits, see alignment E=9e-19 amino acids 557 to 680 (124 residues), 87.3 bits, see alignment E=4.7e-29 PF13188: PAS_8" amino acids 430 to 484 (55 residues), 30.5 bits, see alignment (E = 1.1e-10) PF00989: PAS" amino acids 430 to 543 (114 residues), 46.5 bits, see alignment E=1.6e-15 amino acids 560 to 666 (107 residues), 49.7 bits, see alignment E=1.5e-16 PF08448: PAS_4" amino acids 435 to 549 (115 residues), 38.3 bits, see alignment E=6.2e-13 amino acids 565 to 675 (111 residues), 61 bits, see alignment E=5.4e-20 PF13426: PAS_9" amino acids 440 to 546 (107 residues), 47.1 bits, see alignment E=1.1e-15 amino acids 572 to 672 (101 residues), 56.5 bits, see alignment E=1.4e-18 PF08447: PAS_3" amino acids 582 to 666 (85 residues), 59.6 bits, see alignment 1.3e-19 PF00512: HisKA" amino acids 715 to 777 (63 residues), 30.9 bits, see alignment 1e-10 PF02518: HATPase_c" amino acids 821 to 940 (120 residues), 71.1 bits, see alignment E=4.9e-23 PF00072: Response_reg" amino acids 964 to 1076 (113 residues), 43.9 bits, see alignment E=1.1e-14 amino acids 1155 to 1260 (106 residues), 54.7 bits, see alignment E=5e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_2490)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWG9 at UniProt or InterPro

Protein Sequence (1266 amino acids)

>HSERO_RS12450 histidine kinase (Herbaspirillum seropedicae SmR1)
MADFSWLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARS
MLYNDAFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAPQQAECLAL
LAPPQAATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDLLSDLMEQSP
SFKAVVRGPEHVFERVNSAYFKLFGDRPVIGQPARMALPELLDENLFMLLDRVYQTGQAY
TERGARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERMLAEERLRIVD
RAGEIGIFEWFPDSGRLSVSDRFRRLWGLPPEGEVTAAQLVGMIDEQFHPNLGTARIKEG
GSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTGSRYVGVAFDVTARKLMEQALAAS
EASVRANNAFVRQLLDSTDQGFFSIDSAGIITLCNAAFLQLLGYAAEKDVLGRPIHDVIL
QPSEETQSRTGCAVLRAAREGVSAHVDSENFLRVDGTSFPVQYQTHPVWQDGQLQGALCT
FVDLTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGRYLRVNQALCRMLGRSEEEML
GMTLADVTHPDDVPMNMSLFNRCIEDGRSFTLEKRYLRPDGSTFWVSSDISRIVDGEGRP
QAMIAVSTDITERRRAEEALRELNDTLEQRVVEEILERSRAEAALRQMQKMEAVGQLTGG
VAHDFNNVLQIIGGNLQLLQSDPRLDERSRQRVRIAIGAVDRGAKLSSQLLAFARRQPLQ
PRSINLERVVQNMDDLLRRAVGENIDISTRVAHDLWNTMLDPNQVENLIINTAINARDAM
PSGGRLTVQIDNVRLEDPVFLSQADLAPGEYVELQISDNGAGMSPEVRDRAFEPFFTTKL
EGEGTGLGLSMAYGFVKQSKGHISIHSEQGKGTTIRIYFPRCLDEEVRIDEVRDLTVHGG
DETILVVEDDPNLQLTVIDTLSSLGYRVLKADNGERALEILQSGVAIDLVFTDVVMPGSV
PVTELAQQARLLVPDIEILFTSGYPRDTIVHEGRLDAGVELLSKPYRINQLAQRIRQMLS
QRAHRVELAQVTRERDQAAASATIHVLPRTEREPVAQADPLVREAHGAGGASAAQPLPDY
PRPEPQEDAGGLRLLVVEDNIDSQQLVCELLETLGHQARGVISGEEALQALEEQGFDVLF
TDVNLPGMSGVELAKAALGRFPDLAVIFASGYGTMVARNVGFAAHALPKPYDIDQLQEIL
DKIAAG