Protein Info for HSERO_RS12375 in Herbaspirillum seropedicae SmR1

Annotation: 3-oxoacyl-ACP reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_2475)

MetaCyc: 56% identical to meso-butanediol dehydrogenase [(R)-acetoin-forming] (Serratia marcescens H30)
(S,S)-butanediol dehydrogenase. [EC: 1.1.1.76]; RXN-11032 [EC: 1.1.1.76, 1.1.1.304]; 1.1.1.- [EC: 1.1.1.76, 1.1.1.304]

Predicted SEED Role

No annotation

MetaCyc Pathways

pyruvate fermentation to (S)-acetoin (3/3 steps found)
superpathway of 2,3-butanediol biosynthesis (5/6 steps found)
(S,S)-butanediol biosynthesis (1/1 steps found)
(S,S)-butanediol degradation (1/1 steps found)
meso-butanediol biosynthesis I (1/1 steps found)

KEGG Metabolic Maps

Butanoate metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.304 or 1.1.1.76

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWF4 at UniProt or InterPro

Protein Sequence (261 amino acids)

>HSERO_RS12375 3-oxoacyl-ACP reductase (Herbaspirillum seropedicae SmR1)
MSALNPSRLQRFEGKVVIVTGAASGIGEATARRFSDEGARVLLADRDAAALGKVFDSLPP
ERTAARETDVSHHEQVRQLVDFAIERFGQLDVLVSDAGVFAEGNVTEVSPEDWHRVQATN
VNGVFYGAREALPHLEKTRGCIVNVASVSGLAADWNLSAYNASKGAVCNLTRAMALDFGR
KGVRINAVCPSLTHTAMTADMADDPPLLDKFAERIALGRGADPLEIAAVITFLASPDASF
VNGVNLPVDGGLMASNGQPPQ