Protein Info for HSERO_RS09995 in Herbaspirillum seropedicae SmR1

Annotation: N-acetylglucosaminyldiphospho-UDP N-acetyl-beta-D-mannosaminyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 TIGR00696: glycosyltransferase, WecB/TagA/CpsF family" amino acids 66 to 239 (174 residues), 103 bits, see alignment E=7.7e-34 PF03808: Glyco_tran_WecG" amino acids 67 to 239 (173 residues), 164.9 bits, see alignment E=2.3e-52 PF01740: STAS" amino acids 285 to 361 (77 residues), 33.9 bits, see alignment E=3.4e-12 PF13466: STAS_2" amino acids 290 to 361 (72 residues), 38.8 bits, see alignment E=1.3e-13

Best Hits

KEGG orthology group: K05946, N-acetylglucosaminyldiphosphoundecaprenol [EC: 2.4.1.187] (inferred from 100% identity to hse:Hsero_2000)

Predicted SEED Role

"N-acetylmannosaminyltransferase (EC 2.4.1.187)" in subsystem Teichoic and lipoteichoic acids biosynthesis (EC 2.4.1.187)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.187

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8ISF7 at UniProt or InterPro

Protein Sequence (373 amino acids)

>HSERO_RS09995 N-acetylglucosaminyldiphospho-UDP N-acetyl-beta-D-mannosaminyltransferase (Herbaspirillum seropedicae SmR1)
IAGAPDFQRDVWSILGLPFDRVSLGQAAGILQRAASERRRCFLSTPNLNFAVACLDDAAF
RHSVIQSDLSIADGMPLVWIARALGLPIKERVAGSSLFQALREQRMENGQAPLRVYFFGG
PPGVAQAADEKLNATPSGLRSVGYASPGFGSIEEMSPPQALAHINDSRADFLVVALGAKK
GQAWIQHNLVQLRAPVVSHLGAVVNFVAGTVSRAPRWAQKTGLEWLWRIKEEPKLWRRYF
DDGMALLRLLATRVLPCIWESRRHRPAAALLDEAEIRCRLDGGDCELLFSGALGQANLAR
LRPVLAQAAQGDAPLVLDCTRLQYIDSAALAQLMLLYGDCVRRGRPWAIINASASLRRQI
TLHCADYLLQARA