Protein Info for HSERO_RS09440 in Herbaspirillum seropedicae SmR1

Annotation: exopolyphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02541: Ppx-GppA
  • amino acids 20 to 298 (279 residues), 211.2 bits, E=2.2e-66
• PF21447: Ppx-GppA_III
  • amino acids 306 to 463 (158 residues), 112.4 bits, E=2.1e-36

Best Hits

KEGG orthology group: K01524, exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC: 3.6.1.11 3.6.1.40] (inferred from 100% identity to hse:Hsero_1891)

Predicted SEED Role

"Exopolyphosphatase (EC 3.6.1.11)" in subsystem Phosphate metabolism (EC 3.6.1.11)

MetaCyc Pathways

• ppGpp metabolism (6/6 steps found)
• polyphosphate metabolism (2/2 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.11 or 3.6.1.40

Sequence Analysis Tools

See D8IRS6 at UniProt or InterPro

Protein Sequence (485 amino acids)

>HSERO_RS09440 exopolyphosphatase (Herbaspirillum seropedicae SmR1)
MFAAVDLGSNSFRLHIGKYEDEGIRVIKSARDPIRLAAGIDKTGNLTEQACQSAIDSLTR
FRAILRDYPLTAVRVVATNTLRVAKNAGELLPALERAIGYPVEIISGEEEGRLIYMGVAG
VLADAGEERMVIDIGGGSTEVIRGLGEHIRHVESFGIGTVNQSLAFFPDGAITAAAFERA
IISARSHVEDAVHLFSFDAAKVNVYGSSGTMRAIADTIRRNNMGDGRITLPSLADLMQRL
IDFGHVSQIALDGMKPDRAGVIMGGLAVLIGFMQEFGIEVITPVEAGLRMGVMWDLQLRA
TKADRRDRSVEEFARRFHIDAARAHGVADTALGFFQLLKPATDSYARYLYWSALLHETGL
VVSPTGYHKHSAYMIANADLPGFTTREQRLMSTLILGQKGNLKKISEMLADIDFAKAVLA
LRLAVMFRHAHITLDLEKVRVKLKSRIDLEIRRDYIKEHPSISFWFQKEQEWWAGIGVDF
AVKVI