Protein Info for HSERO_RS08530 in Herbaspirillum seropedicae SmR1

Annotation: glycine/betaine ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 46 to 66 (21 residues), see Phobius details amino acids 79 to 103 (25 residues), see Phobius details amino acids 108 to 125 (18 residues), see Phobius details amino acids 158 to 197 (40 residues), see Phobius details amino acids 204 to 231 (28 residues), see Phobius details PF00528: BPD_transp_1" amino acids 59 to 225 (167 residues), 66.1 bits, see alignment E=1.8e-22

Best Hits

Swiss-Prot: 57% identical to OSMY_SALTY: Osmoprotectant import permease protein OsmY (osmY) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K05846, osmoprotectant transport system permease protein (inferred from 100% identity to hse:Hsero_1713)

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IQW5 at UniProt or InterPro

Protein Sequence (237 amino acids)

>HSERO_RS08530 glycine/betaine ABC transporter permease (Herbaspirillum seropedicae SmR1)
MTRVRHVFAGALGFALVLAGLVWWIGPDVIQKYRGDLIYYTGKHLELVFTSMLLALATGI
PAGIALSRPGAQRSAEKFIQIFNIGNTIPSIAVLALALAFFGIGNGPTILALWLASLLPI
VRNTYEGLKNVPAAMKEAARGIGMKPHQILLRVELPNALPIIVGGVRTALAINVGTAPLS
MLIGGESLGGLIFPGIYLNNHGQLLLGAAATALLALVLDALVTALSGFYLARRGLRT