Protein Info for HSERO_RS07945 in Herbaspirillum seropedicae SmR1

Annotation: chloride channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 572 transmembrane" amino acids 12 to 41 (30 residues), see Phobius details amino acids 61 to 81 (21 residues), see Phobius details amino acids 114 to 130 (17 residues), see Phobius details amino acids 135 to 153 (19 residues), see Phobius details amino acids 160 to 187 (28 residues), see Phobius details amino acids 196 to 214 (19 residues), see Phobius details amino acids 229 to 254 (26 residues), see Phobius details amino acids 266 to 284 (19 residues), see Phobius details amino acids 304 to 324 (21 residues), see Phobius details amino acids 331 to 351 (21 residues), see Phobius details amino acids 357 to 384 (28 residues), see Phobius details amino acids 391 to 410 (20 residues), see Phobius details PF00654: Voltage_CLC" amino acids 73 to 405 (333 residues), 252.6 bits, see alignment E=6.4e-79 PF00571: CBS" amino acids 510 to 556 (47 residues), 28.9 bits, see alignment 1.2e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_1584)

Predicted SEED Role

"Chloride channel protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IQ51 at UniProt or InterPro

Protein Sequence (572 amino acids)

>HSERO_RS07945 chloride channel protein (Herbaspirillum seropedicae SmR1)
MKHKRDYTADRRLPYLCAIALPIGLLSTGAAWLLLKLIALFTNLFYFQRLSLAASTPATH
TLGWIAALLPIAGGLIVGLMARYGSDKIRGHGIPEAIEAILFGKSRMSPKVALLKPLSSG
IVIGSGGPFGAEGPIIMTGGSIGSLLAQLLHLTAAERKTLLVAGACAGMTAIFGTPLAAV
LLAVELLLFELKPRSLLPVALACAVAGFVRPWLVEAGPLFPLDVAAPTPVALLSCLVAGL
ASGVLAAALTLALYRIEDGFHRLRLHWMWWPALGGIAVGLGGLLQPRALGVGYDVIGDLL
HQHMLLSAALALLLVKAVIWLLALGSGTSGGVLAPLLMLGAGLGLVLSPWLPGGSDGLWP
LVCMAGVLGSVLGAPLTAIVFAFGLTHASQALLPLIATTAVAYGVNVLLMKRSIMTEKIA
RRGLHVHREYGVDPLERMHVEELMTAAPQTLAGALPAAEALAWCRAQEHVHRYYPVTDGV
HLVGMLALRALEHADASQPCDTLAQGHEHYLLPHMSARSAAGMMARLGVARLPVVAGPER
RKLVGVLSLSDLARASAAHAEEESVRERLLGG