Protein Info for HSERO_RS07330 in Herbaspirillum seropedicae SmR1

Annotation: major facilitator transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 51 to 76 (26 residues), see Phobius details amino acids 88 to 111 (24 residues), see Phobius details amino acids 117 to 118 (2 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 187 to 206 (20 residues), see Phobius details amino acids 238 to 256 (19 residues), see Phobius details amino acids 276 to 295 (20 residues), see Phobius details amino acids 305 to 326 (22 residues), see Phobius details amino acids 338 to 358 (21 residues), see Phobius details amino acids 368 to 390 (23 residues), see Phobius details amino acids 402 to 419 (18 residues), see Phobius details PF00083: Sugar_tr" amino acids 19 to 419 (401 residues), 108.6 bits, see alignment E=3.8e-35 PF07690: MFS_1" amino acids 21 to 382 (362 residues), 93.9 bits, see alignment E=1e-30

Best Hits

Swiss-Prot: 65% identical to CITA_ECOLX: Citrate-proton symporter (citA) from Escherichia coli

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_1458)

MetaCyc: 66% identical to propane-1,2,3-tricarboxylate-proton symporter (Salmonella enterica enterica serovar Typhimurium str. LT2)
RXN1R65-49

Predicted SEED Role

"metabolite/H symporter, major facilitator superfamily (MFS)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IPF4 at UniProt or InterPro

Protein Sequence (432 amino acids)

>HSERO_RS07330 major facilitator transporter (Herbaspirillum seropedicae SmR1)
MTTTTTNAKHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISKTFFPSDNEFVSLILTFGT
FGAGFLMRPLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGVAAPILVL
TGRLLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQSLS
PVQISDWGWRIPFFIGCMIVPAIFIIRRSLQETDEFLARKRHPSFGEIMSSIAQNWKIVV
AGMMMVVMTTVSFYLITVYTPTFGKNVLKLSASDSLIVTFCVGLSNFCWLPIMGALSDRV
GRRPVLVAFTLLTLLTAYPVMSWLVSDISFKNLLITELWLSFLYASYNGAAVVALTEVMP
AHVRTVGFSLAYSLATAIFGGFTPLVSTWLIETSGDKAAPGYWMSFAAVCGLLATLVLYR
GKSAAATVSPTA