Protein Info for HSERO_RS06790 in Herbaspirillum seropedicae SmR1

Annotation: 2-dehydropantoate 2-reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 PF03807: F420_oxidored" amino acids 16 to 114 (99 residues), 28 bits, see alignment E=4e-10 PF02558: ApbA" amino acids 17 to 182 (166 residues), 88.9 bits, see alignment E=3.9e-29 PF08546: ApbA_C" amino acids 210 to 328 (119 residues), 91.1 bits, see alignment E=1.1e-29

Best Hits

KEGG orthology group: K00077, 2-dehydropantoate 2-reductase [EC: 1.1.1.169] (inferred from 100% identity to hse:Hsero_1353)

Predicted SEED Role

"2-dehydropantoate 2-reductase (EC 1.1.1.169)" in subsystem Coenzyme A Biosynthesis (EC 1.1.1.169)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.169

Use Curated BLAST to search for 1.1.1.169

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IP49 at UniProt or InterPro

Protein Sequence (353 amino acids)

>HSERO_RS06790 2-dehydropantoate 2-reductase (Herbaspirillum seropedicae SmR1)
MSDDSISPSAPSAPLRICIAGAGAIGGTLAVRLAAAGHQVSVLARGQTLQAIREHGLTLH
DLHGTAHARPAADHRPSFGVQDVIFLCAKSQDMAGLLPQVAPMVGETTVVIPTNNGVPWW
YFHREGGRFDGQTVKAVDPEGALAAALPLAQIIGSVLFITAEVESAGVIRSVNPHLMVLG
EPSGEMSERLLRVRAAVESAGIEARATDRIRDKLWTKIIANISTNPLSVITQGTLQQLYG
LPELREVVSQIMRETLLVASSHGARVDIDPLTFLQLGEAMGAFRTSMLQDLERGRPLELA
AIGDAVLEMAERYAIPMPITRAIVSLARFRGEAAQQQRAPQTPAAPQPAARAA