Protein Info for HSERO_RS04820 in Herbaspirillum seropedicae SmR1

Annotation: C4-dicarboxylate ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 transmembrane" amino acids 20 to 37 (18 residues), see Phobius details amino acids 47 to 78 (32 residues), see Phobius details amino acids 95 to 114 (20 residues), see Phobius details amino acids 126 to 153 (28 residues), see Phobius details amino acids 235 to 260 (26 residues), see Phobius details amino acids 291 to 315 (25 residues), see Phobius details amino acids 321 to 338 (18 residues), see Phobius details amino acids 350 to 373 (24 residues), see Phobius details amino acids 379 to 401 (23 residues), see Phobius details amino acids 404 to 428 (25 residues), see Phobius details amino acids 433 to 454 (22 residues), see Phobius details amino acids 473 to 495 (23 residues), see Phobius details PF00939: Na_sulph_symp" amino acids 20 to 501 (482 residues), 469.5 bits, see alignment E=1.5e-144 TIGR00785: transporter, divalent anion:Na+ symporter (DASS) family" amino acids 37 to 495 (459 residues), 383.2 bits, see alignment E=7.6e-119 PF03600: CitMHS" amino acids 57 to 419 (363 residues), 80.8 bits, see alignment E=1e-26

Best Hits

Swiss-Prot: 48% identical to YFLS_BACSU: Putative malate transporter YflS (yflS) from Bacillus subtilis (strain 168)

KEGG orthology group: K03319, divalent anion:Na+ symporter, DASS family (inferred from 100% identity to hse:Hsero_0962)

Predicted SEED Role

"2-oxoglutarate/malate translocator" in subsystem Photorespiration (oxidative C2 cycle)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8J0S4 at UniProt or InterPro

Protein Sequence (501 amino acids)

>HSERO_RS04820 C4-dicarboxylate ABC transporter (Herbaspirillum seropedicae SmR1)
MLAQLKAAFKYFNDAVPFKLVPALIATAVLIALLLTPCPTGLEPKAWALVAIFLTTIVAI
ILKVMPIGVMAMMAIVIVSLSQVTSTSSKGAITDALASFSNPLIWLIVVAILISRGLKKT
GLGRRVGLMFIALLGKRTIGIGYGLAICELVLAPFTPSNTARGGGIVHPIMKSIANAFDS
DPAKGTQNKVGSYLALVNYHANPITSAMFLTATAPNPLVVNYVAKATGHALQLTWTTWAL
CMLLPGLVCLLIMPMVIYLLSPPELKSTPNAVDYARSELDKMGKLGASEKVMLGTFALLL
LLWANVPAMLLGAAFTLDPTVVAFVGLFVLIITGTIDWDDVLSEKSAWDTLVWFGALVML
AEQLNKTGVVAWFSEGMKAAIVASGMGWIAVAAVLLLVFVLSHYFFASTTAHISAMMLAF
LTVGAQLLPPQYVVPFMLMMTAGSGVMMTLTHYATGTSPIIFGSGYVSMGKWWGVGFVMA
VVELLVFATVGMVWWKGLGYW