Protein Info for HSERO_RS03145 in Herbaspirillum seropedicae SmR1

Annotation: poly(A) polymerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 TIGR01942: poly(A) polymerase" amino acids 47 to 470 (424 residues), 485.9 bits, see alignment E=5.1e-150 PF01743: PolyA_pol" amino acids 76 to 201 (126 residues), 133.6 bits, see alignment E=8e-43 PF12627: PolyA_pol_RNAbd" amino acids 229 to 288 (60 residues), 70.6 bits, see alignment E=1.1e-23 PF12626: PolyA_pol_arg_C" amino acids 342 to 460 (119 residues), 136.1 bits, see alignment E=9e-44

Best Hits

KEGG orthology group: K00970, poly(A) polymerase [EC: 2.7.7.19] (inferred from 100% identity to hse:Hsero_0629)

Predicted SEED Role

"Poly(A) polymerase (EC 2.7.7.19)" in subsystem Polyadenylation bacterial (EC 2.7.7.19)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IYI8 at UniProt or InterPro

Protein Sequence (534 amino acids)

>HSERO_RS03145 poly(A) polymerase (Herbaspirillum seropedicae SmR1)
MIKKLIRSILGRGKTAAAAASAEPPAPARKTRAKAGADGKIEPDVLGPKEHGIDPSLVSP
NAVRVTQTLQEAGYKAFIVGGAVRDLLLGIKPKDFDVATNATPEQVKQLFRRAFIIGRRF
QIVHVMFGQELIEVTTFRGASAEAAPKDEHGRVLRDNTFGEQHEDATRRDFTINAMYYDP
ASQAVLDYHGGIADIRDKKLRIIGEPEARYREDPVRMLRVVRFAAKLKFTIDPASSAPIR
VMAPLIDNVPAARVFDEMLKLLMSGHALACLQQLRKEGLHHGLLPLLDVVLEQPLGEKFV
TLALADTDARVKQGKGVSPGFLFASLLWHQVLEKWRAYQAAGEYPIPALHLAADDVLDAQ
TEKLALQRKIASDMRDIWAMQPRFERRVGKAPYKLLEHLRLRAGFDFLLLRCQSGELDAE
LGEWWEAFIAGTGAEREELIARKPADAAGVAAGPKKRKRRGGRSRSRSGGDADFNDTAPA
GDVAPAPAEAPARAESAAPDSDSGASPAPKRRRRRRSSTGGAEGAGGDAGAGSD