Protein Info for HSERO_RS03045 in Herbaspirillum seropedicae SmR1

Annotation: HrcA family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 PF03444: HrcA_DNA-bdg" amino acids 4 to 74 (71 residues), 24.1 bits, see alignment E=2.4e-09 TIGR00331: heat-inducible transcription repressor HrcA" amino acids 4 to 338 (335 residues), 327.2 bits, see alignment E=8e-102 PF01628: HrcA" amino acids 106 to 325 (220 residues), 221.1 bits, see alignment E=1.7e-69

Best Hits

Swiss-Prot: 72% identical to HRCA_BURM1: Heat-inducible transcription repressor HrcA (hrcA) from Burkholderia multivorans (strain ATCC 17616 / 249)

KEGG orthology group: K03705, heat-inducible transcriptional repressor (inferred from 100% identity to hse:Hsero_0609)

Predicted SEED Role

"Heat-inducible transcription repressor HrcA" in subsystem Heat shock dnaK gene cluster extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IYG8 at UniProt or InterPro

Protein Sequence (342 amino acids)

>HSERO_RS03045 HrcA family transcriptional regulator (Herbaspirillum seropedicae SmR1)
MQLDNRARTLLKALVERYIADGQPVGSRALSKLSGLELSPATIRNIMADLEEMGFVASPH
TSAGRVPTPRGYRMFVDTLLTVEAIDESALEGRLQARLQHSTSPQKIITNAAQVLSSLSQ
FAGVVMTPKRESVFQQIEFLRLSEKRILLVIVDQGGDVQNRMLLTEVDYTPSQLTQAANY
INQHYAGQSFDQVRMHLQGELRQLRDDMTALMQAAVEAGSDAMSEEADNNVVISGERNLL
SVTDLSSNMNSLRRLFDMFEQKTGLLQLLDVSSKATGVQIFIGGESQLVPMDDMSIVTAP
YEVNGRIVGTLGVIGPTRMAYERVIPIVDITAKLLSSALSQH