Protein Info for HSERO_RS02795 in Herbaspirillum seropedicae SmR1

Annotation: alcohol dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 PF08240: ADH_N" amino acids 26 to 151 (126 residues), 104.4 bits, see alignment E=3e-34 PF00107: ADH_zinc_N" amino acids 197 to 283 (87 residues), 40.8 bits, see alignment E=2e-14

Best Hits

Swiss-Prot: 67% identical to YBDR_ECOLI: Uncharacterized zinc-type alcohol dehydrogenase-like protein YbdR (ybdR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_0558)

Predicted SEED Role

"Threonine dehydrogenase and related Zn-dependent dehydrogenases" in subsystem Threonine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IYB7 at UniProt or InterPro

Protein Sequence (386 amino acids)

>HSERO_RS02795 alcohol dehydrogenase (Herbaspirillum seropedicae SmR1)
MRALLYHSAHDVRVETVPDPIIQEADDVILKVTATAICGSDLHLYRGKIPATKAGDILGH
EFMGVVVEAGPAIKRLKKGDRVVVPFVIACGQCFFCDQHLYAACETTNPDRGALMNAKGI
RSGAAMFGYSHLYGGMPGGQAEYVRVPKADVGPIRIDSALADEQVLFLSDILPTGYQAVK
NAGVREGSSVAIYGAGPVGQMAAASARMLGAERIFMVDHHAYRLRFAQEQYDVIPVNFDQ
VDPAEYIIANTAGRGVDGVIDAVGFEAKGSVLETAMTTLKLEGSSGQALRHCIASVRRGG
VISVPGVYAGFIHGFLFGDIFEKGVTVKTGQTHVQHYMPELLASIEEGRLRPDAIITHRL
PLEDAARGYQIFNDKLEDCRKVVLTA