Protein Info for HSERO_RS02730 in Herbaspirillum seropedicae SmR1

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 transmembrane" amino acids 37 to 54 (18 residues), see Phobius details amino acids 60 to 81 (22 residues), see Phobius details amino acids 102 to 121 (20 residues), see Phobius details amino acids 127 to 146 (20 residues), see Phobius details amino acids 152 to 169 (18 residues), see Phobius details amino acids 174 to 193 (20 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 220 to 382 (163 residues), 116.1 bits, see alignment E=6.8e-38 PF00990: GGDEF" amino acids 221 to 377 (157 residues), 132.4 bits, see alignment E=1.3e-42 PF00563: EAL" amino acids 407 to 630 (224 residues), 221.7 bits, see alignment E=9.7e-70

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_0548)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IYA7 at UniProt or InterPro

Protein Sequence (650 amino acids)

>HSERO_RS02730 histidine kinase (Herbaspirillum seropedicae SmR1)
MRLSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLW
LGLYFPAVLSVLCSVRLLFWWRNRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFP
YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL
NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN
EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLTACRDPALHLARL
GGDEFALIIDRDLSDAALQEIGQQLCHTLRRAFVLDKAVVQIAASVGVATFPDMAADAAT
LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL
DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR
LSFNLSANDINSSEGMAEIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG
CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC
VVEGLETPQHLAVLRELGAMYGQGYLYARPMAADDVAPWLAQRAARVQAG