Protein Info for HSERO_RS02290 in Herbaspirillum seropedicae SmR1
Annotation: isopenicillin N synthase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 43% identical to HXNY_EMENI: 2-oxoglutarate-Fe(II) type oxidoreductase hxnY (hxnY) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
KEGG orthology group: K06892, (no description) (inferred from 100% identity to hse:Hsero_0459)Predicted SEED Role
"2-Oxobutyrate oxidase, putative" in subsystem Methionine Degradation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See D8IXA9 at UniProt or InterPro
Protein Sequence (328 amino acids)
>HSERO_RS02290 isopenicillin N synthase (Herbaspirillum seropedicae SmR1) MIPYTPPMTARRIPVIDFADAFSPELARREALAWEIHKISRDVGFFYLVNHGVPQALIDG QFDWARRFFALPQASKSAIDMRHSASGYGYERMGAQALDEGSPADLKEGFQFGFDIAPDH PYVLRGLLRYGHNLWPQDLPGFETHSRQYYEAVRALSHRLLGVIALSLEMPEDFFTPVLH TPIATQRMLHYPPQPASAQHNQIGAGAHTDWGLVTILAQDAIGGLEICNAEGDWVSAPPI AGSFVVNIGDLLQRWSNDLYHSNAHRVCNVGNAPRYSLPFFQDGDQAAVVACLPTCCSAE RPARYAPCTIGDYLEMKVKQTFGAVAAA