Protein Info for HSERO_RS02195 in Herbaspirillum seropedicae SmR1

Annotation: sugar ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 transmembrane" amino acids 46 to 67 (22 residues), see Phobius details amino acids 102 to 124 (23 residues), see Phobius details amino acids 136 to 153 (18 residues), see Phobius details amino acids 185 to 208 (24 residues), see Phobius details amino acids 241 to 261 (21 residues), see Phobius details amino acids 289 to 312 (24 residues), see Phobius details PF00528: BPD_transp_1" amino acids 138 to 319 (182 residues), 59.6 bits, see alignment E=1.8e-20

Best Hits

KEGG orthology group: K10228, sorbitol/mannitol transport system permease protein (inferred from 100% identity to hse:Hsero_0441)

MetaCyc: 59% identical to polyol ABC-type transporter permease component MtlF (Pseudomonas fluorescens)
7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]

Predicted SEED Role

"Various polyols ABC transporter, permease component 1" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.M2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IX91 at UniProt or InterPro

Protein Sequence (324 amino acids)

>HSERO_RS02195 sugar ABC transporter permease (Herbaspirillum seropedicae SmR1)
MSTLHSTQVSSTSPMMQSTSQPASRRQQTSPPRKERFNPIRLMQTPSVLILLAWMIVPLA
MTIYFSVNRYNLMAPDQTGFVGLENYAFLLQDPAFWPSIGNTALLIGSVLAISVIGGTLL
AVLFDQPFRGRGIARLLVIGPFFVMPTVAALIWKNMIMHPVYGILAYVMRHLGLEPIDWL
AEYPMLSVIIIVAWQWIPFAFLILLTALQSLDTDQKEAAQLDGAGPVRIFFYIVLPHLKR
AITVVIMIETIFLLSVFAEIFTTTAGGPGTATTNLTFLVYSIGLQQFDIGIASAGGIFAV
VLANIVSFFLVRMLARNLKGVNEK