Protein Info for HSERO_RS01565 in Herbaspirillum seropedicae SmR1

Annotation: hemolysin secretion protein D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 51 to 380 (330 residues), 278.5 bits, see alignment E=3e-87 PF16576: HlyD_D23" amino acids 77 to 300 (224 residues), 57.1 bits, see alignment E=2.4e-19 PF13533: Biotin_lipoyl_2" amino acids 77 to 124 (48 residues), 52.7 bits, see alignment 4.4e-18 PF13437: HlyD_3" amino acids 187 to 297 (111 residues), 34.3 bits, see alignment E=5.2e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_0316)

Predicted SEED Role

"RND efflux system, membrane fusion protein CmeA" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IW44 at UniProt or InterPro

Protein Sequence (399 amino acids)

>HSERO_RS01565 hemolysin secretion protein D (Herbaspirillum seropedicae SmR1)
MQTPAPLRKRFALTATVLAVIALSVGGAISVVGLSANATTAPSAAAAGAPVDVAEVVSRQ
IIDWQSYSGRIEAVDRVEVRPLVGGTLTAVHFKDGALVKKGDVLFTIDPRPYEAEVARAE
AQLAGAEARAGYTASDLARGQRLLSDNAIAKRDFEEKQNASREASANVAAARAALRAARL
NLEYTRITAPVSGRISRAEVTVGNVVNPGAANAPLTTLVSVAKVYASFDVDEQSFLKYVN
PARAAGATVPVELGLANEDGYSRKGRVGSVDNRLDTASGTIRVRAIFDNANSQLVPGLYA
RVRLGGGEPHQAVLIDEKAIGTDQDKRFVMVADKDNHANYRQVVVGAGHDGLVVIEKGLQ
PGERIVVNGLQRIRPGDAITPTVVPMQTAAAPAAGAGKA