Protein Info for HSERO_RS01445 in Herbaspirillum seropedicae SmR1

Annotation: biopolymer transporter TonB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 236 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF13103: TonB_2" amino acids 142 to 223 (82 residues), 26.9 bits, see alignment E=4.1e-10 TIGR01352: TonB family C-terminal domain" amino acids 156 to 224 (69 residues), 38.1 bits, see alignment E=7.5e-14 PF03544: TonB_C" amino acids 161 to 220 (60 residues), 38.4 bits, see alignment E=1.4e-13

Best Hits

KEGG orthology group: K03832, periplasmic protein TonB (inferred from 100% identity to hse:Hsero_0292)

Predicted SEED Role

"Ferric siderophore transport system, periplasmic binding protein TonB" in subsystem Campylobacter Iron Metabolism or Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IW20 at UniProt or InterPro

Protein Sequence (236 amino acids)

>HSERO_RS01445 biopolymer transporter TonB (Herbaspirillum seropedicae SmR1)
MMNLPLLFRFREPLATLPSLVVLAVLIIAGVQKATELKRKEDPQPVQIALMELPPPPPPQ
PKPQVEPPPKPVEPPKKQEAPRPVAKPAPVKQTPAPVDPAPPSANAPVVPAPPSTPAAPP
VQAAPVAPPAPPPVNTANIEQTYVGQLRAHLNSIKRYPTGREASTLRPQGKVRVWFVLRR
DGSVVDSGIESSSNSMLLDDAARKTINRAAFAPFPDDTYKGESTHRFTADLDFIPV