Protein Info for HSERO_RS01295 in Herbaspirillum seropedicae SmR1

Annotation: deoxyuridine 5'-triphosphate nucleotidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 656 transmembrane" amino acids 25 to 45 (21 residues), see Phobius details amino acids 50 to 70 (21 residues), see Phobius details amino acids 100 to 122 (23 residues), see Phobius details amino acids 127 to 146 (20 residues), see Phobius details amino acids 152 to 169 (18 residues), see Phobius details amino acids 175 to 193 (19 residues), see Phobius details amino acids 239 to 257 (19 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 233 to 389 (157 residues), 104.8 bits, see alignment E=2e-34 PF00990: GGDEF" amino acids 235 to 386 (152 residues), 118.3 bits, see alignment E=2.8e-38 PF00563: EAL" amino acids 406 to 640 (235 residues), 212.4 bits, see alignment E=6.8e-67

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_0262)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IVZ0 at UniProt or InterPro

Protein Sequence (656 amino acids)

>HSERO_RS01295 deoxyuridine 5'-triphosphate nucleotidohydrolase (Herbaspirillum seropedicae SmR1)
VQAPAAQLSLQQLIRADQLAALRQTVLLSIPVNMVLGAICTFVAWRAGHLAIALLWLACS
GMVNLLRILACRLPVQRVAALVQRIAAPGAGVIDLNLRVHWMLALCSGLVWAGVALLCAG
YTAPGTLFYLTCVCGITAGAVTHGFAYARIPIAFITPPLLAIIASLVLVEPDTTRVALAA
AVLLYLGALIRGSKVSEGLVSHASALKNEATTASQALEVAHRDLHQFAERMRYQAEHDLL
TGLLGRAGFMAAAQAMAARREEVLCMMFLDLDGFKVINDAYGHDAGDQVLVEVARRLQGC
LPAGATLARLGGDEFVILYALDAQAELPELLARRLIEVVRQPFARLAHRHIGLSLGITLS
DRDDIDEMLVCSDAAMYQAKRRGRNQFCVFNETLNAHLQMKRDVERDLAGALARRELAVW
FQPIVQHDGQTLDGFEALLRWQHGKHGAIAAPDLIEIAALAGLSEELLRFILEEVAGMIA
FLQSSGRSDLRISMNISPREMERLVVDELVVSMLKAHRLPARMLEIEITEETALDLQAAT
QTLVALALQGVRIAIDDFGVGYSSLGFLRQMQVSRVKIDRSFVTGLADQTENQALVSAVL
QLAGSFGFQVVAEGVESAEDLQTLQAMHCHAMQGYYFAPPMPAAQARARIEALAQA