Protein Info for HSERO_RS00975 in Herbaspirillum seropedicae SmR1

Annotation: alpha,alpha-trehalose-phosphate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 TIGR02400: alpha,alpha-trehalose-phosphate synthase (UDP-forming)" amino acids 3 to 455 (453 residues), 574.5 bits, see alignment E=7.7e-177 PF00982: Glyco_transf_20" amino acids 16 to 454 (439 residues), 403.5 bits, see alignment E=6.2e-125

Best Hits

Swiss-Prot: 51% identical to OTSA_SINFN: Trehalose-6-phosphate synthase (otsA) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K00697, alpha,alpha-trehalose-phosphate synthase (UDP-forming) [EC: 2.4.1.15] (inferred from 100% identity to hse:Hsero_0196)

Predicted SEED Role

"Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15)" in subsystem Trehalose Biosynthesis (EC 2.4.1.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IV03 at UniProt or InterPro

Protein Sequence (464 amino acids)

>HSERO_RS00975 alpha,alpha-trehalose-phosphate synthase (Herbaspirillum seropedicae SmR1)
MGRLVVVSNRLADPRKPAAGGLAVALGETLKKTGGLWFGWSGKVIENGTPGEGEVRVNQA
GPVTLAELDLSQEDHDAYYRGYANGVLWPVFHYRLDLAHFEAGHLGGYRRVNQLFARKLF
PLLKRDDIVWIHDYHLIPLAAELRAMGCEARIGFFLHIPLPPPPILTAIPSHEWLMRALF
AYDLVGFQNHADLQHFAQYVQAEATAEPVGPNQFRAFNRTVHANAFPIGIDVAEFQRLGQ
AKEARDTYESTKAEYSRRRLLIGVDRLDYSKGLPQRIRAFRELLRLYPENRHSATLLQIA
SPSREDVEAYGDIQRELESLCGSINGDFGDFDWMPIRYIHRTVARRRLPGLYRACAVALV
TPLRDGMNLVAKEFVAAQDPDDPGVLVLSRFAGAAEQMKAALIINPYDTHGTAQVIQQAL
QMSQSERRERHAALMENIRQFDVHWWCREFLDTLRSSRAAPVES