Protein Info for HSERO_RS00890 in Herbaspirillum seropedicae SmR1

Updated annotation (from data): L-proline ABC transporter, permease component 2
Rationale: Specifically important for utilizing proline as a carbon or nitrogen source
Original annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 46 to 67 (22 residues), see Phobius details amino acids 73 to 94 (22 residues), see Phobius details amino acids 123 to 145 (23 residues), see Phobius details amino acids 153 to 170 (18 residues), see Phobius details amino acids 221 to 238 (18 residues), see Phobius details amino acids 271 to 294 (24 residues), see Phobius details amino acids 306 to 333 (28 residues), see Phobius details amino acids 361 to 379 (19 residues), see Phobius details PF02653: BPD_transp_2" amino acids 42 to 371 (330 residues), 157.1 bits, see alignment E=2.5e-50

Best Hits

KEGG orthology group: K01998, branched-chain amino acid transport system permease protein (inferred from 100% identity to hse:Hsero_1189)

Predicted SEED Role

"Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IUY5 at UniProt or InterPro

Protein Sequence (404 amino acids)

>HSERO_RS00890 L-proline ABC transporter, permease component 2 (Herbaspirillum seropedicae SmR1)
MALLTFDMKRNPQQARISLLLLLALMIVFPFVAQQFGNSWVRIMDVALLYIMLALGLNVV
VGFAGLLDLGYIAFYAIGAYSAGLLASPQFAAVIESFVNTYPSVGNFLVWLCGPEIVQNG
IHLSLWLIVPISAFLAALFGALLGAPTLKLRGDYLAIVTLGFGEIIRIFMNNLNAPVNIT
NGPQGINLIDPIKVFGVSLAGEPGSGSMVKVFGMSMPSVNAYYFLFLLLCIGVIFFSVRL
QDSRLGRAWVAIREDEIAAKAMGINTRNVKLLAFAMGASFGGVAGAMFGAFQGFVSPESF
SLTESIAVLAMVVLGGIGHIPGVVLGGVILAALPEVLRHVVEPVQMAIFGKVWIDAEVLR
QLLYGLAMVVIMLTRPAGLWPSPRHEDRPEADHTQVGTTGEVKA