Protein Info for HSERO_RS00880 in Herbaspirillum seropedicae SmR1

Annotation: ornithine cyclodeaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02423: OCD_Mu_crystall
  • amino acids 15 to 307 (293 residues), 114.4 bits, E=5.5e-37
• PF01488: Shikimate_DH
  • amino acids 125 to 210 (86 residues), 26 bits, E=8.5e-10

Best Hits

KEGG orthology group: K01750, ornithine cyclodeaminase [EC: 4.3.1.12] (inferred from 100% identity to hse:Hsero_0176)

Predicted SEED Role

"Ornithine cyclodeaminase (EC 4.3.1.12)" in subsystem Arginine and Ornithine Degradation (EC 4.3.1.12)

MetaCyc Pathways

• L-arginine degradation VII (arginase 3 pathway) (2/2 steps found)
• L-ornithine degradation I (L-proline biosynthesis) (1/1 steps found)
• L-proline biosynthesis II (from arginine) (1/2 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

Compare fitness of predicted isozymes for: 4.3.1.12

Use Curated BLAST to search for 4.3.1.12

Sequence Analysis Tools

See D8IUY3 at UniProt or InterPro

Protein Sequence (312 amino acids)

>HSERO_RS00880 ornithine cyclodeaminase (Herbaspirillum seropedicae SmR1)
MHILDPRQTAQALPYAALVDALARATQELADGRIRAPERQVVPIDAASVLLGMPAIADDL
SVTKLITVHADNARHQLPAIQGEVIAFETQTGRRLALMDGPTVTARRTAAMSMLGIRTLL
PRQPQSALLIGTGVQSAAHADALVEFFGVRQFWIVARDLARTQAFCRALSERHPQAVASP
LPAQMLQQDLPHTDVVIALTTSRSAVIPEHIAADTLAIGVGAFKPDMVEFPASLLHARRI
VVDDLAGAHHEAGDLIQAGVDWSGVVAIADVVAGRAPAAALASGAALPVFKTVGQAAWDL
AAARVMRATLGL