Protein Info for HSERO_RS00295 in Herbaspirillum seropedicae SmR1

Annotation: potassium transporter Kup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details transmembrane" amino acids 51 to 76 (26 residues), see Phobius details amino acids 111 to 136 (26 residues), see Phobius details amino acids 148 to 167 (20 residues), see Phobius details amino acids 178 to 198 (21 residues), see Phobius details amino acids 222 to 243 (22 residues), see Phobius details amino acids 255 to 274 (20 residues), see Phobius details amino acids 297 to 327 (31 residues), see Phobius details amino acids 347 to 367 (21 residues), see Phobius details amino acids 373 to 395 (23 residues), see Phobius details amino acids 406 to 427 (22 residues), see Phobius details amino acids 433 to 452 (20 residues), see Phobius details PF02705: K_trans" amino acids 22 to 554 (533 residues), 736.4 bits, see alignment E=9.1e-226

Best Hits

Swiss-Prot: 72% identical to KUP_CUPNJ: Probable potassium transport system protein kup (kup) from Cupriavidus necator (strain JMP 134 / LMG 1197)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 100% identity to hse:Hsero_0060)

MetaCyc: 53% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8ITU9 at UniProt or InterPro

Protein Sequence (633 amino acids)

>HSERO_RS00295 potassium transporter Kup (Herbaspirillum seropedicae SmR1)
MSSSHTNPSLSLRSSKFHLITLAALGVVFGDIGTSPLYALKECFSPDHGIAFSPGAVLGI
ISMLFWSISIVVTIKYVMFVLRADNNGEGGVLALMALSLRSALSGSPRAKLLMMLGVFGA
CMFYGDVVITPAISVLSAVEGLEIAAPQTAHAVIPLTLVIVVILFLIQRHGTSVVGRFFG
PVMFLWFFSLALLGLYNIVKAPEVLVAINPYYAVHFMAEHSLQAFIVLGSVVLVLTGAEA
LYADMGHFGIKPIRYAWLFTVMPSLLINYFGQGANLIANPDAIKNPFYLMIPDPLVLPMV
VLATCATVIASQAVISGAFSLTSQAILLGFVPRMRILHTSEDEQGQIYIPLINWMLLVVV
VAVVLAFKKSDNLAAAYGVAVTTTMVITTMLLGVVMRHIWKWRMPAVVAAISCFLVVDVA
FFAANLLKLTEGGWFPLVIGGAAFFLLMTWYSGRMLLRMRIKDDGIPIEPFIEGLLAHPP
HRVGGTAVFMTGNIATVPVALLHNLKHNRILHERVFFLKISIWDVPYVADSERLTMKELG
GDVYLLRAAFGFKEAPEVQKVMTLTEQQFGHHFDLMDTSFFLARDTVVPSKLLGMSLWRE
RLFAWMYQNGAKPSDFFHIPANRVVELGTKVEI