Protein Info for HMPREF1078_RS17625 in Parabacteroides merdae CL09T00C40

Annotation: glycosyl hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 960 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF17132: Glyco_hydro_106" amino acids 52 to 142 (91 residues), 39.1 bits, see alignment E=1.8e-14 amino acids 211 to 770 (560 residues), 151.3 bits, see alignment E=2.1e-48

Best Hits

Predicted SEED Role

"glycoside hydrolase family 2, sugar binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (960 amino acids)

>HMPREF1078_RS17625 glycosyl hydrolase (Parabacteroides merdae CL09T00C40)
MQRRSFIKQSVLWTAGCAVGSRMSLWGTVSAADEVKGTVLRSGELYKLFRDPQSIYRPFV
RWWWNGDKVEADELKRELHILKEAGIGGVEINPVKFPGNDTDDLGKKSLPWLSDEWIDML
KVAFDEAKSLDMTCDLIVGSGWPFGAEFLKGDERADVVVNYSEKLSGPIDYEVSRDGLFC
AADPAISSPFLGKKMELVSLQLVPEPFGSLDQAIDLMDKEVDGTFKFKVPDGKYVLFALV
KIRGFLEVINGAPGATGPVLNHFNKPAVQKYLNNMSDKIQNRLGPLSGNIRSLFTDSMEL
EGSNWSYDMAEEFKKRRGYDVQPYLPFILFKMGSMGNVLTYEPKVRFTPELDDTIQRVRY
DFEYTKAELLRERFTQTYLDWCKGLNVKSRAQAYGRGFFPLESSLDYDIPECESWTMTWL
RHRLGEEMSEEDYRRGRAYTMVNKYVSSAAHLRGKRLVSCEEMTNTYTVFNMTLELLKIG
GDQTAISGVTHSIFHGFNYSPKEAPFPGWIRYGAYYNENNNWWPYFKYYTAYKGRMASAL
QHGTMYADIAILHPIADMWSTLGMQNEPFPATTNVKYKTLVWEAIHKNGSGCDYVSESII
RDAEMKDGYLCYGPRKYKTLFLIEVESMEPATAHKLYDFVASGGRIFCIEAYPHKSVGLK
DHDKHDKEVQEWVEKMKQMDGRFILLHKPEKDFVGWYQGVQKDYGLTPYMTIEKPDPYLM
QNRYQGDNREEMFFFSYAHRYNSHQTRISFSNEVVKGRQGWVWDLETGERYRLPLDAANS
FLFDFGPADSLLIVFDKQKRGNDYKPHPVSGEDLKDLSSDWDVEFRHSRENTVQNTHFDK
LKDLKDTDYVNFCGTIVYRKKVNVSSPVGMVLNLGLVHGVSEVFVNGQSCGVKWYGRRIH
LVSARLKQGENSVEVHVVTVMGNYMKTLKDNKIAQAWTRRQDVVQPAGLVGPVTAYRIKN