Protein Info for HMPREF1078_RS15610 in Parabacteroides merdae CL09T00C40

Annotation: helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 transmembrane" amino acids 6 to 30 (25 residues), see Phobius details amino acids 44 to 62 (19 residues), see Phobius details amino acids 74 to 96 (23 residues), see Phobius details amino acids 108 to 129 (22 residues), see Phobius details amino acids 149 to 170 (22 residues), see Phobius details amino acids 192 to 214 (23 residues), see Phobius details amino acids 223 to 242 (20 residues), see Phobius details PF12833: HTH_18" amino acids 311 to 390 (80 residues), 54.1 bits, see alignment E=8e-19

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (391 amino acids)

>HMPREF1078_RS15610 helix-turn-helix domain-containing protein (Parabacteroides merdae CL09T00C40)
MDIHTLYIIAYATSTTSCLGSCAILLFLNYGNIETNPVYLKARRILAFATFLVAIGLLIS
LTTRKWQPVGWDIASFPVTLIASSQTLLFTFSLILLFNEQYATRQRILLHATPSLLFTLA
YAGACLIWKDHPVYAYSEWKSLVTNPPSLIRTLYLLAYIIQSGIYAKLFLHERHTYLSLL
GGVKTEDRWLKLGQVTSAFFLASGIGLCTLSLALNPHLPHEITVTFLFTVFYFAFGIFYA
NFSSTYRDVRTRIREQNSAFSPPAGADMEELICYLQPDDDNNRLFKDIEAYFQKEQPYLD
PDFRISDLPRTIGANPHKLSTAVGRATGLTVQDYVLRLRIGHSADLLLLPENAERTIEDI
AFSSGFQSTSTYNRNFLKLMKTTPSRFRSRT