Protein Info for HMPREF1078_RS15165 in Parabacteroides merdae CL09T00C40

Annotation: glycoside hydrolase family 127 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 617 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF07944: Glyco_hydro_127" amino acids 38 to 416 (379 residues), 380.7 bits, see alignment E=1.1e-117 PF20736: Glyco_hydro127M" amino acids 427 to 520 (94 residues), 83.4 bits, see alignment E=1.6e-27 PF20737: Glyco_hydro127C" amino acids 522 to 613 (92 residues), 88.2 bits, see alignment E=3.6e-29

Best Hits

KEGG orthology group: K09955, hypothetical protein (inferred from 76% identity to pdi:BDI_3335)

Predicted SEED Role

"Putative glycosyl hydrolase of unknown function (DUF1680)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (617 amino acids)

>HMPREF1078_RS15165 glycoside hydrolase family 127 protein (Parabacteroides merdae CL09T00C40)
MKQYFVLLFACMALWGCGGQDQIETPPLKIIDQIDFSHVHIRDNFWSPRLAKHTSATLPV
CIDQIENQTGRMQNFENAARGTGKHSGIFFDDSDVYKALEGIAYSLINNPDPELEKKADE
WIDKIAAAQQPDGYINTFYTLTGQDKRWNNMDKHEMYCAGHMMEAAVAYYQATGKRKLLD
VSIRMADHMMELFGPGKRHWVPGHEEIELALVKIYRTTGQEKYLDFANWLLEERGHGHGS
MGGEGKWDPAYYQDVIPVRELTDISGHAVRCMYLYCGMADVAALKKDTAYVEALNRLWDD
VVLRNMYVTGGIGSSRHNEGFTEDYDLPNLDAYCETCASVGMVYWNQRMNQFTGDSKYID
VLERSMYNGALAGVSLAGDRFFYVNPLESNGDHHRQAWYGCACCPSQISRFLPSIGNYIY
GTSDKALWVNLFIGNTTEVTIDGKKVVMKQETDYPWDGLVKLTVTSEQPLGKELRIRIPG
WCKSYTLSVNGNKVDSTTDKGYTVIKEWKTGDLIVLNMDMPVEKVSADPRVRQNTGKRAL
QRGPLVYCLEETDNAKDFADLALTPTSSFEVKDEPDNLGGIRSIKAISNGQTLHFIPYYA
WDNRKAGKMKVWIDYQE