Protein Info for HMPREF1078_RS13505 in Parabacteroides merdae CL09T00C40

Annotation: ABC-F family ATP-binding cassette domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 PF00005: ABC_tran" amino acids 21 to 180 (160 residues), 83 bits, see alignment E=6.5e-27 amino acids 329 to 463 (135 residues), 66.8 bits, see alignment E=6.6e-22 PF12848: ABC_tran_Xtn" amino acids 219 to 296 (78 residues), 43.7 bits, see alignment E=4.9e-15 PF16326: ABC_tran_CTD" amino acids 559 to 625 (67 residues), 58.5 bits, see alignment E=1.3e-19

Best Hits

KEGG orthology group: None (inferred from 88% identity to pdi:BDI_2033)

Predicted SEED Role

"COG0488: ATPase components of ABC transporters with duplicated ATPase domains" in subsystem Folate Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (627 amino acids)

>HMPREF1078_RS13505 ABC-F family ATP-binding cassette domain-containing protein (Parabacteroides merdae CL09T00C40)
MISYLQIDKLTKSFGDLVLFEDITFGIAQGQKVGLIAKNGTGKTTLLNIIAGKEDYDNGA
VVFRNDLRVGYLEQMPHYPDGLTVLQACFYSPNETVRLIAEYEQAMASGDHSNLEDILLR
MDNLKAWDYEQRTKQILGQLKIHNFDQKVETLSGGQLKRVALANVLITDPELIILDEPTN
HLDLEMTEWLEGYLSRANISILMVTHDRYFLDRVCSEIIEIDRKQIYQYKGNYSYYLEKR
QERMDALNAEVDRASNLLRKELDWMRRQPQARGTKAKYRIDAFYELEKKAKQQHEAGNVN
LDVKASYIGSKIFEAEHVSKRFGDLKIVEDFNYIFARYEKMGIVGNNGTGKSTFIKMLMG
EVEPDSGCFDVGETVRFGYYSQDGLQFDEQMKVIDVVQNIAEYVDLGDGKKMGVSQFLNY
FLFAPEKQHNYVYKLSGGEKRRLYLCTVLMRSPNFLVLDEPTNDLDIVTLNVLEEYLRNF
KGCAIVVSHDRYFMDKVVDHLLVFRGNADIKDFPGNYTQYREWKEVQDQLEKETEAARQA
RMAPTVEKTSRLEKVQKKKLTFKERKEFEALEVEISLLEAEKAELETAMSSGTLSNDELL
AKSERIAKVIEEIDEKTMRWLELSELA