Protein Info for HMPREF1078_RS13445 in Parabacteroides merdae CL09T00C40

Annotation: Gfo/Idh/MocA family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 388 PF01408: GFO_IDH_MocA" amino acids 7 to 137 (131 residues), 59.6 bits, see alignment E=7.5e-20 PF22725: GFO_IDH_MocA_C3" amino acids 147 to 278 (132 residues), 91.5 bits, see alignment E=6.2e-30 PF02894: GFO_IDH_MocA_C" amino acids 150 to 375 (226 residues), 54.5 bits, see alignment E=2.1e-18

Best Hits

KEGG orthology group: None (inferred from 62% identity to shg:Sph21_1618)

Predicted SEED Role

"Nucleoside-diphosphate-sugar epimerases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (388 amino acids)

>HMPREF1078_RS13445 Gfo/Idh/MocA family oxidoreductase (Parabacteroides merdae CL09T00C40)
MKNRKLRMGMVGGGSDAFIGAIHRRAAFMDNQIELVCGCFSVDPEISKSSGLSYFLPEDR
IYSTYQEMFEHEMTLPEGERMDFVTIVTPNRWHFEPAMMALERGFHVVVDKPMTFSLEEA
KQLQKKVEETGLVLALTHVYSAYPAVKEAKARIAKGELGKLRRVYVEYTQGWLSERIELL
GGNNAGWRTDPKRSGKAGCIGDIGTHAWHLSEYITGLKVKELCADLKAFVPGRPIDDDGA
AFLRYENDVTGVLTATQIGTGEANNIRIRIYGEKGGLEWRQMEPNTLTLRWRDRPTEILD
IGNNGYLTPEALWNTRTPAGHPEGFIEAFANIYRNFSLTVRAIKNGETPSGDCLDFPTVY
DGVRGMQFIETMVEAGYNDNVKWQKWID