Protein Info for HMPREF1078_RS11815 in Parabacteroides merdae CL09T00C40

Annotation: gamma-glutamyl-gamma-aminobutyrate hydrolase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 592 PF07722: Peptidase_C26" amino acids 38 to 237 (200 residues), 205.9 bits, see alignment E=1e-64 PF00117: GATase" amino acids 114 to 251 (138 residues), 71 bits, see alignment E=1.6e-23 PF01244: Peptidase_M19" amino acids 268 to 582 (315 residues), 336.9 bits, see alignment E=1.9e-104

Best Hits

KEGG orthology group: None (inferred from 76% identity to pdi:BDI_3549)

Predicted SEED Role

"Membrane dipeptidase precursor (EC 3.4.13.19)" (EC 3.4.13.19)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.13.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (592 amino acids)

>HMPREF1078_RS11815 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein (Parabacteroides merdae CL09T00C40)
MKLRRPNLEAIYREVDHYIPKKENLQPPRIGISANRKDGLSCIAETYVQAVLKAGGAPVL
IPVITDIEALTAIVNGLDGLVMSGGGDINPLYMQEEPIPALQDVDTYRDEYDLILLRLAT
NRQLPVMGICRGHQILNVAFGGNVYQDIHTQHNQKLLKHSQTLSREQVSHSVALNEGPSK
LRTMLDSEKELLVNSFHHQAIKEPAPEFITTATAPDGINEAMEHPEKEIFSVQWHPEAMA
ANDDEQMLKLFKHHVESSRLFKKAKYIHHRNVMLDSHTDTPMIFPGEFNIGLKEGGKVNL
PFMEEGLIDATIMVAYIPQGPRDDASLLKATDFAMNRLQEIHRQMELNRTRMCIAYTPQE
VHVLKAAGKKAIMLGVENGYAIGKDIENITRFRKMGVSYITLCHNGSNDICDSARGDAEW
NGLSPFGKEVVRKMNETGVLVDISHAAESTFYDALETSTYPIIASHSSARALCNHPRNLT
DEQLKALAEQGGVAQICLYKGFINEDAEKASLSDAIRHIDHIVDLIGINHVGIGSDFDGD
GELIGCRASNELINITMRLLKEGYTENDIAKIWGGNLLRVMNKAQSAPDNSL