Protein Info for HMPREF1078_RS11785 in Parabacteroides merdae CL09T00C40

Annotation: DNA repair protein RecO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 PF11967: RecO_N" amino acids 1 to 79 (79 residues), 55.7 bits, see alignment E=4.1e-19 TIGR00613: DNA repair protein RecO" amino acids 4 to 154 (151 residues), 62.2 bits, see alignment E=2.5e-21 PF02565: RecO_C" amino acids 89 to 226 (138 residues), 65.6 bits, see alignment E=4.7e-22

Best Hits

Swiss-Prot: 46% identical to RECO_AZOPC: DNA repair protein RecO (recO) from Azobacteroides pseudotrichonymphae genomovar. CFP2

KEGG orthology group: K03584, DNA repair protein RecO (recombination protein O) (inferred from 78% identity to pdi:BDI_3555)

Predicted SEED Role

"DNA recombination and repair protein RecO" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (241 amino acids)

>HMPREF1078_RS11785 DNA repair protein RecO (Parabacteroides merdae CL09T00C40)
MLCKTRGIVLHSIPYNDKYSIIYMYTEAFGRASYLVARSRGKKSSVSKALFMPLSVVEME
VEHLNKRDLHRIRETKLCYPLTEVFCNPVKNILALFLSEILFRVVKETEPDSRLFEYLFE
SIQLLELSDKGVANFHLVFLLRLLHYLGIYPNVESYVAGSCFDMLNGVFVDRIPMHRHYL
NRQESVVLARLLKISFENMSLYSFSRQDRVSVINRILEYYRLHLPDFPEIKSLSVMQSLF
D