Protein Info for HMPREF1078_RS10230 in Parabacteroides merdae CL09T00C40

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 transmembrane" amino acids 12 to 38 (27 residues), see Phobius details amino acids 48 to 73 (26 residues), see Phobius details amino acids 89 to 120 (32 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 170 to 191 (22 residues), see Phobius details amino acids 219 to 238 (20 residues), see Phobius details amino acids 259 to 277 (19 residues), see Phobius details amino acids 288 to 305 (18 residues), see Phobius details amino acids 311 to 334 (24 residues), see Phobius details amino acids 343 to 365 (23 residues), see Phobius details amino acids 376 to 395 (20 residues), see Phobius details PF07690: MFS_1" amino acids 20 to 243 (224 residues), 83 bits, see alignment E=1e-27 amino acids 226 to 399 (174 residues), 63.5 bits, see alignment E=8.6e-22

Best Hits

KEGG orthology group: K08223, MFS transporter, FSR family, fosmidomycin resistance protein (inferred from 75% identity to bth:BT_1438)

Predicted SEED Role

"Fosmidomycin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>HMPREF1078_RS10230 MFS transporter (Parabacteroides merdae CL09T00C40)
MEQNKVQATTGITFRILVALSICHCLNDTLQSVISAVYPLFKEDLGLSFAQIGLITLVYQ
SAASVCQPLTGLFFDKWPSAWSLPTGMSFTLVGLLSLAFANTLPLVLCSVALVGIGSSVF
HPEASRLTSLASGGKRGLAQSLFQVGGNLGGSLGPLLAAVFVAPYGRRHIALFTILAFTA
IMVMIPVGHWYKSFLLRLRKAEGETLKTSVCRPLPMGKTVFSIAILLILIFSKYIYMASL
NSYYTFYLIHKFGVSVQASQLYLFVFLIATAIGTLLGGPIGDRVGRKYVIWASILGAAPF
TLIMPHVENLYLTTILSFCVGLTLSSAFPAILVYAQELLPYKLGLISGLFFGFAFGVAGI
ASAVLGNMADRYGIEAVYNVCGYMPLIGLVTWFLPDLKKKR