Protein Info for HMPREF1078_RS10215 in Parabacteroides merdae CL09T00C40

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 transmembrane" amino acids 29 to 49 (21 residues), see Phobius details amino acids 197 to 217 (21 residues), see Phobius details amino acids 245 to 269 (25 residues), see Phobius details amino acids 275 to 300 (26 residues), see Phobius details amino acids 302 to 325 (24 residues), see Phobius details amino acids 361 to 381 (21 residues), see Phobius details PF12698: ABC2_membrane_3" amino acids 34 to 375 (342 residues), 160.9 bits, see alignment E=2.4e-51

Best Hits

KEGG orthology group: K01992, ABC-2 type transport system permease protein (inferred from 76% identity to pdi:BDI_1533)

Predicted SEED Role

"ABC-type multidrug transport system, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (399 amino acids)

>HMPREF1078_RS10215 ABC transporter permease (Parabacteroides merdae CL09T00C40)
MNNFKNSVMNCQFVRVFRRELVRMVSRRLYFGVCVVLPLFCIFFMSTIFGNGQMENIPVG
VVDEDNTSMSREVVRTVEAVPTFKVTHRYVDETAARRATQSKEIYGYLVIPTGFTADAIA
GRQATLAYYYHYALLSVGGEVRGAFEAVLRQLSMAPVVMQATALGIGEERVATFLLPVKA
SSHPLFNPDLDYSVYLSNPFFFILFQVIILLTTVYVIGGEVKFGTGAEWLSTAGGNIMTA
VVGKLLPYTVIFSLMSILANYVMFGLMHIPFSCGFWPLNLTAILFVVSTQALAVFIFSVF
PVLSIIISIVSMVGSLGATLSGVTFPVPSMYAPVHYASYLFPVRHFTEIYQNLLYGDYGF
AWTWMNYVALLCFLLPALLMLPRLKKAIVNEEMWRHLVS