Protein Info for HMPREF1078_RS06705 in Parabacteroides merdae CL09T00C40

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF20434: BD-FAE" amino acids 40 to 223 (184 residues), 72.8 bits, see alignment E=5.8e-24 PF07859: Abhydrolase_3" amino acids 58 to 206 (149 residues), 52.4 bits, see alignment E=1.2e-17 PF00326: Peptidase_S9" amino acids 116 to 263 (148 residues), 51.5 bits, see alignment E=2e-17

Best Hits

KEGG orthology group: None (inferred from 42% identity to pru:PRU_2630)

Predicted SEED Role

"putative xylanase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (270 amino acids)

>HMPREF1078_RS06705 alpha/beta hydrolase (Parabacteroides merdae CL09T00C40)
MKHILLLLLSFFVPVVWGQQVEQFKLWPDKPEAGEAEIFVYHPAKGGKAAPAVLICPGGG
YRGLAMNHEGHDMAKWYASNGFVAVVLKYRMPEGVHTIPLSDAEKAMSVIRGNAAKWNLD
ANKVGVIGSSAGGHLAASLSTLAADANRPDFAILYYPVISFDNMTTHGGSKKNLLGTDIE
NKELVDRYSLQKQVDDKTPKTLLLLSDDDQTVPPLNSILYYTALNEHHIPASLYMFPSGG
HGWGFRYDFTYYQEVKDLIQKWLTYIKITD