Protein Info for HMPREF1078_RS06655 in Parabacteroides merdae CL09T00C40

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1138 PF07660: STN" amino acids 21 to 68 (48 residues), 35.4 bits, see alignment (E = 1.8e-12) TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 82 to 1138 (1057 residues), 873.4 bits, see alignment E=2.8e-266 PF13620: CarboxypepD_reg" amino acids 83 to 152 (70 residues), 40 bits, see alignment 1e-13 PF13715: CarbopepD_reg_2" amino acids 83 to 164 (82 residues), 63.2 bits, see alignment 4.7e-21 PF07715: Plug" amino acids 172 to 277 (106 residues), 62.6 bits, see alignment E=1.1e-20 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 253 to 283 (31 residues), 58.8 bits, see alignment (E = 3.4e-20) PF00593: TonB_dep_Rec" amino acids 498 to 901 (404 residues), 48.4 bits, see alignment E=3.4e-16

Best Hits

Predicted SEED Role

"SusC, outer membrane protein involved in starch binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1138 amino acids)

>HMPREF1078_RS06655 TonB-dependent receptor (Parabacteroides merdae CL09T00C40)
MENTTVQEVLTTIEQKSGFYFTYNLEQVKVTRKVTVNFKDKTVPEVLDELFAKENIHYVI
NDKHIALYKGNERQVALQAKKDIKGVVTDKNGEPIPGANIIEKGNPTNGTITDVDGNYTL
SVFGNSVLVASYIGYNRIEIQVKDRSVVDITLSEDTQALEEVVVVGYSTQKKVNLTGSVS
TVNFESMSSRPVTDASQALSGASPGLQIMQSSGQPNAESFSYNIRGVGTLNSSSPLILVD
GMEQSISMVNPSDIANVSILKDAASCAIYGNRGANGVILITTKNGTEGKISVTYDGTVSY
NEPFKIVHTISDYVQYMKLMNESSNNLGNSDIFSQSSIDLWEAAKADPNGISASGYPNYV
AYPNTDWWDEIYTKQWMQKHTISLNGKEKKTGYSMSFSYIDNPGIMKNTGYNRYMGRVNL
YSDITDWLRVGTRTSGNVTDQEVSVTSYNGSSHINSMNTEKMVPCIYPYYDGKYGAPEGP
EEDPQSHNGLWDNVLNGFDKYSQLYTEWYAQVKFLKYFTYNFDFYYQDLRRERKVSDASI
GKFSFSKGAYSTGADDPSTLYTRMYYTRTNRTKLNHLLNYNQSFGIHDVSAMVGYEEETY
DYRETNVSKLGLTDAAVNDLDAATTPYSTAGYGTEYAARSVFGRANYAYKSRYLLEFNLR
YDGSSRFSPDYRWGAFPSFSAGWRMNEELWLKPVQWLTNLKLRASWGKLGNNAIGNYDWQ
SVYSAANYSTGQALTSGIAITSIANAALTWEETAVTNVGLDFGFFDNKLHGNIDVYNKLT
TGILYTPDMYMVMGNATAPKANIAEVTNRGVELELGWRDNIGRDFSYSIKGQFSFNKNFV
SKYKGKLEKGWNKGHTEYSTNIGDVSTGSTTRVIEGRQINEFYLPNVYNGNGSYFNADGT
VNINGGPKDGMIRTENDMQWLQAMQAAGYTFQPYNNIAKNALWYGEYIYADANGDGVYGN
SYDSEFQGTSTTPKYNFGIQASANWKDFDFSMTWGGSAGFSIYYYGKARNSSETTYGYAI
PDAVANDHYFYDPENPSDPRTNQSSKQPRLVNVSGAQSSASSSLHLEKGNFIKLRNLTLG
YTMPKSISKKFYVERLRVYASGENLFAITGFSGMDPEMRVSMGYSTMRQYAFGINLTF