Protein Info for HMPREF1078_RS06450 in Parabacteroides merdae CL09T00C40

Annotation: L-fucose/L-arabinose isomerase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 transmembrane" amino acids 75 to 93 (19 residues), see Phobius details PF11762: Arabinose_Iso_C" amino acids 333 to 470 (138 residues), 26.4 bits, see alignment E=5.1e-10 PF02952: Fucose_iso_C" amino acids 382 to 473 (92 residues), 32.5 bits, see alignment E=6.7e-12

Best Hits

KEGG orthology group: None (inferred from 70% identity to bth:BT_2909)

Predicted SEED Role

"putative L-arabinose isomerase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (476 amino acids)

>HMPREF1078_RS06450 L-fucose/L-arabinose isomerase family protein (Parabacteroides merdae CL09T00C40)
MNTTKKEVKVGLIGVGLNTYWNQFEGLLSRLTDYQRMIKERMSGLQATVIDGGMVDSPEK
AAQTAEVLKSEDIEILFIFISTYALSSTILPIAQRIKIPVILLNIQPVAAINYDYINGLG
DRGKMTGEWLAHCQACSTPEFACVFNRAGIKYDILTGYLEEPYVWNEIENWIDAVRAVQG
MRNNRMGILGHYYCGMLDVYTDITRQSFTFGTHIELLEMCELKAYRDAVTEDERTAKRLE
FSMKFEVDPHCEEYELDRAARTSVALDKLAEAHNLSSMAYYYEGWKGNDYENIVTSVIAG
NTLLTGRGIPVAGECEVKNVQAMKLLSLLDAGGSFSEPYAIDFNDDVVLWGHDGPAHFAI
AEGKVSLVPLPVYHGKPGKGLSIQMRVKQGPVTFLSVCENNDGVFLLIAEGESTDGPTLH
IGNTNSRYRFSCGARTFMNRWSKAGPSHHCAIGIGHVADKLKKIAFLLDIPVIQVC