Protein Info for HMPREF1078_RS04680 in Parabacteroides merdae CL09T00C40

Annotation: FtsX-like permease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 411 transmembrane" amino acids 20 to 49 (30 residues), see Phobius details amino acids 278 to 304 (27 residues), see Phobius details amino acids 326 to 352 (27 residues), see Phobius details amino acids 382 to 401 (20 residues), see Phobius details PF12704: MacB_PCD" amino acids 25 to 251 (227 residues), 43.5 bits, see alignment E=4.7e-15 PF02687: FtsX" amino acids 282 to 406 (125 residues), 57.9 bits, see alignment E=1e-19

Best Hits

KEGG orthology group: K09808, lipoprotein-releasing system permease protein (inferred from 70% identity to pdi:BDI_3305)

Predicted SEED Role

"Lipoprotein releasing system transmembrane protein LolC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (411 amino acids)

>HMPREF1078_RS04680 FtsX-like permease family protein (Parabacteroides merdae CL09T00C40)
MNFPFYIARRYLFSKKSHNAINIISMVSVCGVVVATMALVCALSVLNGFVGLVSSMLGNF
DPELKIQPVHGKVFDPTLPAVREVKELPEVALFCEVLQDNAQVRYRDRQITATVKGVDDT
FGRLTRIDSILVDSREGSFVLSDEVANYANLGVGTAFSLGVRPNYADPLEIYAPKRNEKV
NLANPVASLNLEYAFVGGVYATNQQMYDENFVLLPLPMVRSLFDYEKEVSAIELSLVPGA
DINSVKSRIKSLLGDDFSVKDRYEQQEASFRMMQGEKWMIFLILCFILILALFNVIGSLS
MLMIEKKEDVRTLRNMGADDRLIRRIFLFEGWMISGLGALIGIVIGLALCLLQQELGIIK
LGQAAGSFIIDAYPVRVEAGDILIVFITVLSIGFLAAWYPVHYLGKKWLTR