Protein Info for HMPREF1078_RS03490 in Parabacteroides merdae CL09T00C40

Annotation: response regulator transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 PF12833: HTH_18" amino acids 220 to 296 (77 residues), 75.4 bits, see alignment E=3.6e-25 PF00165: HTH_AraC" amino acids 261 to 297 (37 residues), 38.8 bits, see alignment 8e-14

Best Hits

KEGG orthology group: None (inferred from 60% identity to bhl:Bache_1496)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (299 amino acids)

>HMPREF1078_RS03490 response regulator transcription factor (Parabacteroides merdae CL09T00C40)
MEKIIKLNTVKDYNDFLGIDTPHPLVGVIDASKIKPLHHIRKSIGFYVIYLKDIKCADQI
KYGRKFYDFQEETLVFAAPGQVIGNDDTGEPFQPKGWWLTFQPELLHGTPLNRHMQDYTF
FSYAVNEALHLSKQERQTVIDCMMKIDDEIKGATDRHSNLIVVSAIELLLNYCIRFYDRQ
FITRKKENKDTLSSFEALLNDYFTSDKPSKFGTPTVAYCADQLHLSANYFGDLIKKETGS
SAQEYILAKTMDTAKEWLADPDKSISDVAYALGYQYPQYFSKAFKRIVGCSPNEYRTLN