Protein Info for HMPREF1078_RS02580 in Parabacteroides merdae CL09T00C40

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1115 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 708 to 724 (17 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 52 to 1115 (1064 residues), 870.2 bits, see alignment E=2.5e-265 PF13620: CarboxypepD_reg" amino acids 53 to 111 (59 residues), 36.8 bits, see alignment 8.3e-13 PF13715: CarbopepD_reg_2" amino acids 54 to 134 (81 residues), 60.3 bits, see alignment 2.9e-20 PF07715: Plug" amino acids 142 to 246 (105 residues), 72.5 bits, see alignment E=7.7e-24 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 222 to 252 (31 residues), 59.1 bits, see alignment (E = 2.8e-20) PF00593: TonB_dep_Rec" amino acids 455 to 919 (465 residues), 55.9 bits, see alignment E=1.4e-18

Best Hits

KEGG orthology group: None (inferred from 62% identity to sli:Slin_4979)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1115 amino acids)

>HMPREF1078_RS02580 TonB-dependent receptor (Parabacteroides merdae CL09T00C40)
MEKRVRILCQKGLLLKSSFLFLSISAMPALAIGGNTLKIDNTDEVVVLQKGKTIRGTVED
ALGPITGANVVIKGSTIGVITDIDGRFVLENVPSNAILQISFMGYVPQEVKVGNLTSFEI
RLIEDTQMLDEVVVVGYGTQKKVNLTGAITQVTSKEMENRPVPKVTQMLQGVMPNVNITF
STAQPGAGGSVQVRGRGSVNGGEPLILIDGVPGDINRINPNDVESVSVLKDAAASAIYGA
RGAFGVVLITTKNAQSGKMSVTYNGFFATSKPTVSTDFITCGYESVMLNDEAFRRTTGNT
YTRYTEEDYAELEARRYDKIENPERPWVVVKNVNGKDIYNYYGNWDWWDFLYKDNQSSQS
HNISLSGGDDKLNFLLSGNYYTQDGIMKVNTDKFTSYTFHSKINAQLFPFLKVYNNTQYY
DQTYRYTGKEGGANANFLNTTVHALPCYAPINPDGTYTYNTLKNNYSIGDGMNAMLLDGK
NGGSKGVHEFRTTFGGILDLGNYFKLNVDYTYQFYMADDWYRSAVVQYSIQPGILQDVPN
YNVDQYKKTNWFDPMHVFNAYLNYNQTFGKHSVGATAGVNYETKKHNRLYASRKNLISES
LNDLNLGTGDMEVGGGQYQYVLFGAFVRANYNYDERYLVEFNGRYDGTSRYKKGYRYGFF
PSASAAWRVSEEAFFDDWKDHINNLKVRLSYGTLGNQLMGSSSTSSNYYPYISMMGMSLS
SWLINGQKTQNVSSPNPIIDNLTWEKATTTNIGLDLSFFEGCLNFSGDYYIRNTTDMLIP
GETLPGVFGATSPKQNAGDMRTKGYEFSLSWNDQFEVAGKPFKYGISFGLGDATSEITKF
ATESTMSNPNYDPRNAKITDNYVGKKFGEIWGYRIDGFFKSDEEAANWKIDQTQVNSQIK
KSPGEWGHLRAGDLKFVDLNNDGKITPGLGTLKDPGDMEVIGNSEPRYNYNFNLNASWNG
IDVSALFQGIGRRDWYPASNADKFWGPFSRPYFSFVPEDFVSKLWSEDNPDSYFPVLRGY
TALNGGGCLNSPNDKYIQNIGYLRLKNLVIGYTLPKEWIQKAYIQNLRVYVSGENLITWT
PFETDYIDPEQPIADSNGRSYPLSKTFSVGLDITF