Protein Info for HMPREF1058_RS16095 in Phocaeicola vulgatus CL09T03C04

Annotation: putative DNA binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 513 PF04326: SLFN_AlbA_2" amino acids 13 to 128 (116 residues), 85.8 bits, see alignment E=6.8e-28 PF13749: HATPase_c_4" amino acids 285 to 377 (93 residues), 87.3 bits, see alignment E=1.2e-28 PF08279: HTH_11" amino acids 455 to 498 (44 residues), 26 bits, see alignment 1.4e-09

Best Hits

KEGG orthology group: K03655, ATP-dependent DNA helicase RecG [EC: 3.6.4.12] (inferred from 100% identity to bvu:BVU_2385)

Predicted SEED Role

"ATP-dependent DNA helicase"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9J617 at UniProt or InterPro

Protein Sequence (513 amino acids)

>HMPREF1058_RS16095 putative DNA binding domain-containing protein (Phocaeicola vulgatus CL09T03C04)
MQIQNNTLIAECSAYDFKEMLERKKVKSWLKSVSAFANTDGGSLFYGVNDNGVIVGLENP
QADADFISEMIKARLDPVPEVQLIPIEHEGHTLLEVKVKAGTLTPYYYYQDGTRTAYVRV
GNESVECNSQQLLSLVLKGTHMTWDSLPTQVDASKHSFIILANTFREQTHQEWNDKYLES
FGLVTPDGKLTNAGLLFVDNCTVFQSRIFCTRWTGLYKDDAISSVEHRANLVLLLKYGMD
FIKNYTMSGWVKMPNYRLNLPDYSDRAIFEGLVNHLIHRDYTVMGGEVHIDIYDDRVELV
SPGAMLDGTQIQDRDIYKVPSMRRNPVIADMFTQLDYMEKRGSGLRKMRELTEKLPNFLQ
GKEPQYQTEATSFYTTFYNLNWGDNGRMPVEEVANRVNSTLEKYPVNKESSVEKFGVNTK
EFGVNEESSVEKFGVNADKFGDTSETQKKVSKTAQKIIDLVISDPSITADNMANKIGVTK
RAIEKNIKSLRGMGILVHEGSDKAGYWRIIVKP