Protein Info for HMPREF1058_RS15175 in Phocaeicola vulgatus CL09T03C04

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 999 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 23 to 999 (977 residues), 862.5 bits, see alignment E=5.6e-263 PF13620: CarboxypepD_reg" amino acids 23 to 79 (57 residues), 34.7 bits, see alignment 2.8e-12 PF13715: CarbopepD_reg_2" amino acids 25 to 103 (79 residues), 62.5 bits, see alignment E=4.6e-21 PF07715: Plug" amino acids 111 to 215 (105 residues), 63.1 bits, see alignment E=5e-21 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 191 to 221 (31 residues), 65.5 bits, see alignment (E = 2.7e-22)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_2227)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9UHM5 at UniProt or InterPro

Protein Sequence (999 amino acids)

>HMPREF1058_RS15175 TonB-dependent receptor (Phocaeicola vulgatus CL09T03C04)
MIKKLLVFFLTIFTMTAYAQNVTMTGTVVDTDNLPLIGVNVVIKGTSTGTTTDLDGKFTL
TGENGQTLVFSYIGMTLQEIVYKGKPLHVIMKDDSKALEEVVIIGYQTVKKSDLTGAVAV
VDTKEMKKSSAGTLVSQMQGLATGVNVRSSGRAGEDASIQIRGVGSLSNNAPLWVVDGMI
TDPGVDFNPADVESIQILKDASAAAIYGSRAANGVIIVTTKKGVSGPMKVNVSVKETLEW
SPKFDLMNAAEYIKYNDIAYKEAIKDGIASITTTQKHSEYDTNWQDEVLKTALVQDYNVS
LSGGGDSGSYFVSAGYYNNDGVSYGNTFDRYSFRVNTQGKKGWFSFGENLAYSLTNTDPN
QTNTYNDFLRMMPTIPVYDENNPGGYGYGDAAKYNTFGVNPIARENLEKRHMKQNRLNGS
LWLEFKPFEFLSYKFNGGVDLYFYENSWFRGEGNWQQNQEHRDPESQKARDNTYNMLIEH
TLNFNKDFGKHHVDAVLGTTYQHHEWEGLWASRLNFPMLGNGDYLIVLNAGQSNQQNTNS
ISENAMISYLGRVNYIYDDKYYLTATFRRDGTSRLAKENRWGNFPSVSAAWRISKESFFK
VPWIDDLKIRGNWGRLGNASIGDWDYVGTINQSIVTVFGGAIVPGATQVKLVNTNLVWET
KETVNIGFDASFLNSRLTFSAEYYHSKTKDVLTEMPIAISTGNQEGAPKANAASLRNRGF
ELSLGWKDQVSDFKYGALLNITTLSNKVLSLGYEKPFIDSGQARTRLNGPLAEFFLYKTD
GIFKTQEQIDNYVTPDGEPIMISGKRPQLGDVKYIDTDNNGQITADDRQFCGSPWAKMQM
SLVLNAEWKDFDFSMMWNGQFGNKIYNVSKWQGRLFSDNSNYLRFKKGEEPYQVNQNSDT
PRIIYGDQRNSWDADRFLENGSYFRLKNISIGYNLKKEWLKNLGIDKLRLYATGSNLLTF
TGYSGLDPDFINTNIWNSGTDSFSYPNTRSVMFGLDLTF