Protein Info for HMPREF1058_RS14570 in Phocaeicola vulgatus CL09T03C04

Annotation: AhpC/TSA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF14289: DUF4369" amino acids 24 to 128 (105 residues), 29.2 bits, see alignment E=3.3e-10 PF08534: Redoxin" amino acids 246 to 370 (125 residues), 63.8 bits, see alignment E=4.9e-21 PF00578: AhpC-TSA" amino acids 247 to 363 (117 residues), 76 bits, see alignment E=7.7e-25 PF00085: Thioredoxin" amino acids 260 to 319 (60 residues), 38.1 bits, see alignment E=3.8e-13 PF13098: Thioredoxin_2" amino acids 270 to 368 (99 residues), 29.3 bits, see alignment E=2.7e-10 PF13905: Thioredoxin_8" amino acids 271 to 361 (91 residues), 56.3 bits, see alignment E=1e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_2009)

Predicted SEED Role

"Thiol:disulfide interchange protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9A377 at UniProt or InterPro

Protein Sequence (381 amino acids)

>HMPREF1058_RS14570 AhpC/TSA family protein (Phocaeicola vulgatus CL09T03C04)
MKNLVYALVGAGFMIACQPSDQPEISGMLTGIESDTLLVQSFPVNDRDSRRTDTIAMQNG
SFAFNLGDSVLKQVYIYGKPSVKPNEDGSIPAISMKAVNFLLLPGQPIKISGSLDEYKLE
GGSFYDDYNEVLEDCKAYSHKIDSLNVVCMDMEKKGIPGDSIRKVYASAKEWYGNILKIK
SDYVRQNPDKDVSVYVMSQLTRDQLGDAFNVLTDRVKEGMMAPLYQRMREGYEKELARDK
AKEAMKPGNPAPEFTLKDLDGKNFDLSSLRGKYVVLDFWGSWCGWCIKGIPEMKKAYEKY
KGKIEFVEIDCNDTEDKWKKAVAEHQLPWINVRNIGEPDVAVMYGVSGYPTKYVIDPEGK
IAKQVVGEDPEFYMYLDALMK