Protein Info for HMPREF1058_RS12270 in Phocaeicola vulgatus CL09T03C04

Annotation: L-fucose:H+ symporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 13 to 33 (21 residues), see Phobius details amino acids 56 to 77 (22 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 109 to 126 (18 residues), see Phobius details amino acids 147 to 169 (23 residues), see Phobius details amino acids 199 to 219 (21 residues), see Phobius details amino acids 252 to 274 (23 residues), see Phobius details amino acids 294 to 314 (21 residues), see Phobius details amino acids 321 to 339 (19 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 377 to 397 (21 residues), see Phobius details amino acids 407 to 428 (22 residues), see Phobius details TIGR00885: L-fucose:H+ symporter permease" amino acids 16 to 430 (415 residues), 652.8 bits, see alignment E=1.3e-200 PF07690: MFS_1" amino acids 25 to 385 (361 residues), 64.7 bits, see alignment E=3.8e-22

Best Hits

KEGG orthology group: K02429, MFS transporter, FHS family, L-fucose permease (inferred from 100% identity to bvu:BVU_1372)

Predicted SEED Role

"Fucose permease" in subsystem L-fucose utilization or L-fucose utilization temp

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9UCV7 at UniProt or InterPro

Protein Sequence (437 amino acids)

>HMPREF1058_RS12270 L-fucose:H+ symporter permease (Phocaeicola vulgatus CL09T03C04)
MKDTDQPILYKDGVSYVLPFILVTCCFALWGFANDITNPMVKAFSKIFRMSVTDGALVQV
AFYGGYFAMAFPAAMFIRKYSYKAGILLGLGLYAVGALLFFPAKMTGSYYPFLLAYFILT
CGLSFLETSSNPYILSMGTEATATRRLNLAQSFNPMGSLLGMYVAMNFIQAKLNPMDTAE
RAQLNPAEFAMVRDADLSVLIAPYLTIGIVILVMLLVIRFTQMPKNGDQSHSINFGPTLK
RIFSIHHYREGVVAQFFYVGAQIMCWTFIIQYGTRLFMSQGMEEKAAEVLSQEYNIIAMV
IFCISRFICTFILRYLNPGKLLAILAIAGCCFTAGVIFFQDIWGMYCLVAVSACMSLMFP
TIYGIALTGLGDDAKFGAAGLIMAILGGSVLPPLQASIIDMNTIWNMPAVNVSFILPFIC
FVVITIYGHRSYQRGKY