Protein Info for HMPREF1058_RS11750 in Phocaeicola vulgatus CL09T03C04

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 PF00106: adh_short" amino acids 10 to 211 (202 residues), 167.2 bits, see alignment E=6.6e-53 PF01370: Epimerase" amino acids 12 to 123 (112 residues), 32.3 bits, see alignment E=1.4e-11 PF08659: KR" amino acids 12 to 177 (166 residues), 53.2 bits, see alignment E=7.4e-18 PF13561: adh_short_C2" amino acids 21 to 266 (246 residues), 160.7 bits, see alignment E=9.2e-51

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_1261)

Predicted SEED Role

"D-mannonate oxidoreductase (EC 1.1.1.57)" in subsystem D-Galacturonate and D-Glucuronate Utilization (EC 1.1.1.57)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.57

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9UAZ6 at UniProt or InterPro

Protein Sequence (270 amino acids)

>HMPREF1058_RS11750 SDR family oxidoreductase (Phocaeicola vulgatus CL09T03C04)
MNNLFSVKDQVVVITGGTGVLGKAIAAHLAEEGAKVVILGRKAEVGNAIVNEIKAKGGEA
MFLVTNVLDEAILEQNLKDILAAYGRVDALLNAAGGNMPGATIAPTGNFFDLKVDEFQKV
LNLNLTGTILPTQVFLKPMVEQKKGAIVNFSSMAAFRPMTRVCGYAAAKAGISNFTAFMA
NEVATKFGEGIRVNAIAPGFFLTEQNRTLLTNEDGTYTQRGNDVIRQTPFKRFGKAEELC
GTIQYLISDASSFVTGTVAVVDGGFNAFAM