Protein Info for HMPREF1058_RS08400 in Phocaeicola vulgatus CL09T03C04

Annotation: family 43 glycosylhydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 647 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00251: Glyco_hydro_32N" amino acids 32 to 136 (105 residues), 30.3 bits, see alignment E=3.4e-11 PF04616: Glyco_hydro_43" amino acids 84 to 266 (183 residues), 40.3 bits, see alignment E=2.6e-14 amino acids 340 to 640 (301 residues), 226.2 bits, see alignment E=5.9e-71

Best Hits

KEGG orthology group: None (inferred from 98% identity to bvu:BVU_0497)

Predicted SEED Role

"Hypothetical glycoside hydrolase, family 43, similar to arabinosidase" in subsystem L-Arabinose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9U6W0 at UniProt or InterPro

Protein Sequence (647 amino acids)

>HMPREF1058_RS08400 family 43 glycosylhydrolase (Phocaeicola vulgatus CL09T03C04)
MKNKFFITLFACLLPWMAGAQQTISKQNNVAEKDYIAYLFTYFTGNHISEEAVCYAVSTD
GYTYWALNDNKPVIDSKIISFTGGVRDPHILRCEDGKTFYMVVTDMVSDNGWDSNRAMVL
LKSTDLVNWNHSVINMQKRYAGQEKLKRVWAPQTIFDAEAGKYLVYWSMKYGDGADVIYY
AYANKEFTDLEGEPKPLFIPENKKSCIDGDIVYKDGIYHLFYKTEGHGNGIRVATTRSLT
SGQWEEEPDYKQQTPEAVEGAGTFKLIGQNKYILMYDVYMKGKYQFTETTDLKNFKVIDS
EVKMNFHPRHGTIIPITRAELKRITDKWPSKEMGNMTIPNNPVLQGFHADPEILYSHQTK
KYYIYSTTDGQPGWGGWYFSVFSSDNLKDWKDEGVMLDLKSDQVAWADGNAWAPCIEEKM
VDGKYKYFFYFSGNPVAGGGKQIGVAVADSPIGPFKDLGHPIITESPVGHGQQIDVDVFT
DPVSGKSYLYWGNGYMAGAELNEDMVSIKKNTLTVLTPKGGSLKDYAFREAAYVFYRNGL
YYFMWSVDDTGSPNYHVAYGTSKSPLGPIKVAKKPVVLIQDPAKEIYGPAHNAVLQIPGT
DEWYIVYHRINKNFIDREKGPGVHREVCIDRMEFNPDGTIRKVVPTL