Protein Info for HMPREF1058_RS07705 in Phocaeicola vulgatus CL09T03C04

Annotation: ComEC/Rec2 family competence protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 639 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 49 to 70 (22 residues), see Phobius details amino acids 213 to 230 (18 residues), see Phobius details amino acids 249 to 269 (21 residues), see Phobius details amino acids 277 to 297 (21 residues), see Phobius details amino acids 303 to 319 (17 residues), see Phobius details amino acids 326 to 343 (18 residues), see Phobius details amino acids 349 to 367 (19 residues), see Phobius details amino acids 379 to 400 (22 residues), see Phobius details amino acids 408 to 429 (22 residues), see Phobius details amino acids 431 to 453 (23 residues), see Phobius details amino acids 474 to 494 (21 residues), see Phobius details amino acids 501 to 521 (21 residues), see Phobius details PF13567: DUF4131" amino acids 25 to 178 (154 residues), 74 bits, see alignment E=1.2e-24 PF03772: Competence" amino acids 226 to 494 (269 residues), 208.7 bits, see alignment E=1.1e-65 TIGR00360: ComEC/Rec2-related protein" amino acids 247 to 425 (179 residues), 92.5 bits, see alignment E=1.9e-30

Best Hits

KEGG orthology group: K02238, competence protein ComEC (inferred from 99% identity to bvu:BVU_0049)

Predicted SEED Role

"DNA internalization-related competence protein ComEC/Rec2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9U682 at UniProt or InterPro

Protein Sequence (639 amino acids)

>HMPREF1058_RS07705 ComEC/Rec2 family competence protein (Phocaeicola vulgatus CL09T03C04)
MFRLTIPLVAGIFVSDHFFQGALPVLVSGTGILGCLIGLIVLMKWQGYLSRWLFGGMVFM
FLFCVGALLLQQKWQRVDYEWSSRKNMYQGVIVDVPQEKAKTYLCKLRIDKEMSERGMLP
VNRMILVYIMKDSLSVNLRCGDHLNFYTRISTPEREVIPGEFDYAAYLFRQQISGTAVIF
PGYWQWTGKKSALTWKQRAGVWREKILDSYRKWGFLGDEFAVLSALTVGYKEELSEDLRE
TYQVAGVSHILALSGMHIAVLWGLLCWILRPLDRSCLLRWVKCGIIVLLLWTFAFLVGLP
PSVIRAVVMCMLMTAARAAGERTLSLNTLSVAAFFMLLYNPFYLFDTGFQLSFLAVLSIL
FIYPVISRYWRVRHPVPRYIWGIVAVSLAAQLGTAPVVIYKFAYFPVYFLPANLIVAPLV
LVIIYGSVASFVLSPFTVLHIWVVKGLNGVLRLLNDSMQWVGDLPVSHSGDIHLSLLQVG
ILYVLLFVVLFYLLSPSRKTLITVLCGINLFIGFSGCLYYMKEESFQLILAHSQVKVSPQ
KDVWQQDSIYHYKGMNICVLVDNRWRSRSVDSLLDIDYMYLCKGFKGKIAPLQKIFKIRT
VILDASLGGYRLNLLKDECRGLGLDYIDMSPKGSYRILL