Protein Info for HMPREF1058_RS05630 in Phocaeicola vulgatus CL09T03C04

Annotation: RNA polymerase sigma-70 factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 171 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 8 to 160 (153 residues), 89.3 bits, see alignment E=2.1e-29 TIGR02985: RNA polymerase sigma-70 factor, Bacteroides expansion family 1" amino acids 9 to 160 (152 residues), 136.9 bits, see alignment E=7.5e-44 PF04542: Sigma70_r2" amino acids 12 to 77 (66 residues), 45.7 bits, see alignment E=6.8e-16 PF08281: Sigma70_r4_2" amino acids 107 to 156 (50 residues), 59.1 bits, see alignment E=3.9e-20 PF04545: Sigma70_r4" amino acids 111 to 160 (50 residues), 30.1 bits, see alignment E=4.2e-11

Best Hits

KEGG orthology group: None (inferred from 50% identity to pru:PRU_2159)

Predicted SEED Role

"RNA polymerase ECF-type sigma factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZLL6 at UniProt or InterPro

Protein Sequence (171 amino acids)

>HMPREF1058_RS05630 RNA polymerase sigma-70 factor (Phocaeicola vulgatus CL09T03C04)
MHRLTIDIDETFKYHYRSLCLYVLHYVHDTDIAEDIVQDSFSALWEKLSISGAKIENVRA
YLYTTARNRSLDYLKKEEIYDPNLSPSDFEDTLSDEEAEERSFREAQMWTAIDALPERCR
EIFLLNKRDGMKYREIAAKFQISVNTVDNHISKALRLIREGAQKVYAFLFN