Protein Info for HMPREF1058_RS05470 in Phocaeicola vulgatus CL09T03C04

Annotation: carboxymuconolactone decarboxylase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 535 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02627: CMD" amino acids 23 to 86 (64 residues), 28.3 bits, see alignment E=2.2e-10 amino acids 142 to 211 (70 residues), 46.6 bits, see alignment E=4.2e-16 PF02129: Peptidase_S15" amino acids 249 to 430 (182 residues), 35.5 bits, see alignment E=1.3e-12 PF01738: DLH" amino acids 268 to 373 (106 residues), 28.6 bits, see alignment E=1.6e-10

Best Hits

KEGG orthology group: K06889, (no description) (inferred from 96% identity to bth:BT_1121)

Predicted SEED Role

"Dienelactone hydrolase and related enzymes"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9U2R7 at UniProt or InterPro

Protein Sequence (535 amino acids)

>HMPREF1058_RS05470 carboxymuconolactone decarboxylase family protein (Phocaeicola vulgatus CL09T03C04)
MNKLITTIACLICSIVYTQAQNQDNMLSKKEQSIAAISMYAARGNQDSLKVVLAGGLDCG
LTVSEEKEVLTQLYAYCGFPRSMGALVTLMNLTKERAAQGIKDEAGREPSPVKSSDMFVV
GGQNQLKLFGRPARGEVLTFAPALDQFLKAHLFGDIFSRDNLDWRTRELSTVAALSVMDG
VKNELNTHIAHAKHNGVTQAQIDEILSMAARCRNGMVLSESDEPAKTFQTDPAITVRKVF
YKNRYDIMLCAEMYLPKDINEAQHYAALIIGHPFGAVKEQCSGLYAQEMARRGFVTLAFD
ASYQGESGGEPRHTVSPDALVEDFSASVDWLGLQPFVDRKRIGVIGICGSGGFAVCAASL
DPRIKALATVSMYDMGRATRNGLGDSMTDEQRRKLLDEVAEQRWKEAETGEARIRFGTPE
KLPENANAVQKEFFDYYRNPLRGYHPRYQGTRFTSQAALMNFYPFAMIKEISPRPVLFIA
GEYAHSRYFSEDAYQEAGEPKELYIVPGSNHVDLYDRMDKIPFEKISEFFQHALR