Protein Info for HMPREF1058_RS02395 in Phocaeicola vulgatus CL09T03C04

Annotation: ABC-F family ATP-binding cassette domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 PF00005: ABC_tran" amino acids 18 to 192 (175 residues), 92.2 bits, see alignment E=1.5e-29 amino acids 344 to 474 (131 residues), 77.6 bits, see alignment E=5.3e-25 PF12848: ABC_tran_Xtn" amino acids 231 to 313 (83 residues), 88.1 bits, see alignment E=1.1e-28

Best Hits

KEGG orthology group: K06158, ATP-binding cassette, sub-family F, member 3 (inferred from 100% identity to bvu:BVU_0307)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9TWE9 at UniProt or InterPro

Protein Sequence (544 amino acids)

>HMPREF1058_RS02395 ABC-F family ATP-binding cassette domain-containing protein (Phocaeicola vulgatus CL09T03C04)
MISVDGLTVEFGGTTLFSDISFQINEKDRIALMGKNGAGKSTLLKILAGVRQPSRGKVSA
PKDCVIAYLPQHLMTEDGRTVFEEASQAFAHLHAMEAEIEAINKELETRTDYESDSYMEL
IEKVSAMSEKFYSIDLTHFEEDVEKALLGLGFMREDFNRPTSDFSGGWRMRIELAKLLLQ
NPDVLLLDEPTNHLDIESIQWLEDFLVNSAKAVIVISHDRKFVDNITTRTIEVTMGRIYD
YKVNYSQYLILRKERREQQMKQYEEQQKMIQETKDFIERFKGTYSKTLQVQSRVKMLEKL
ELVEVDEEDTSALRLKFPPSPRSGNYPVIMDGVGKTYGDHVVFKNASLTIERGDKVAFVG
KNGEGKSTLVKCIMREIEHEGTLTLGHNVQIGYFAQNQASLLDENLTVFQTIDDVAKGEI
RNKIRDLLGAFMFGGPEASMKKVKVLSGGERTRLAMIKLLLEPVNLLILDEPTNHLDMKT
KDILKQALMDFDGTLIVVSHDRDFLDGLVTKVYEFGNKKVKEHLCGIYEFLETKKMESLQ
ELEK