Protein Info for H281DRAFT_06533 in Paraburkholderia bryophila 376MFSha3.1

Annotation: sensor domain CHASE2-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 859 transmembrane" amino acids 24 to 44 (21 residues), see Phobius details amino acids 325 to 345 (21 residues), see Phobius details amino acids 352 to 371 (20 residues), see Phobius details amino acids 376 to 395 (20 residues), see Phobius details PF05226: CHASE2" amino acids 35 to 333 (299 residues), 204.4 bits, see alignment E=3.9e-64 PF02518: HATPase_c" amino acids 714 to 843 (130 residues), 78.6 bits, see alignment E=7.6e-26

Best Hits

KEGG orthology group: None (inferred from 82% identity to bug:BC1001_5799)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (859 amino acids)

>H281DRAFT_06533 sensor domain CHASE2-containing protein (Paraburkholderia bryophila 376MFSha3.1)
LPNTSTRLSLDPRARLGRRAGRRFLIEWAAIGCLGLVVIALSSLGRMSASVDHLVYDRLL
SLHAQAVLPDIVVLEIDNESIAQLGRWPWPRSVHARLLKQVAKAKPAAVVYDVLFTETNP
DDAELARAIALSPTYLPVLLTDAGQGAPAVVVEPVAPLVRAAAGLGHINLEVDSDGIVRS
VAQFEGDADSRWPQLMLTVARAAERGALGLNVQPARRASLESASDASDRGAGAHNDAASD
GRFLIPFSPNAQSYEKLSFASVLAGQVPPEKLRGRIVVIGVTASGLYDRFATPVSGALGP
LPGVYIHANVLDTLLTGREVAPAARWLLLLVSLAPLAALLAGFLVLSPRRSLLLTGALCL
LAMSGSAILLYGAQLWLSPVPAILGVVAVYPIWNWRRLEMTMAYLRKELQRLADEPHLLP
QTPQRRRQFGGDVLEQHMALMAQAAQRVQDMKRFMWDSLDSMPEPILVSDMQGIVLIANH
AARAHFARLGAPMPEGRSMQAVLGGLTFVKAIDSGAGADAENDLLARAHWPALLDPTSRE
FAALMAQGVEVRDADGRDHLLRYANCTNAQGETTGWIAGLVDVSALHAAERQREDALRLL
SHDMRSPQASILALVEIERAREKPVLARGLLERIERYAQRALTLADDFVQLARAESQTYL
LEPVNLAELMIDASDEVWPQAHAKRIALHTETDLSAEGRDMDDNGDEGHWICADRSLLTR
ALVNILNNAVKYSPPDTHITCELSNEVPARTSATAGFTTAVASDRVTRRVSCTILDQGYG
IPQDQQAQLFERFRRFHETERPEVGGAGLGMAFVKTVVTRHGGEVNVVSAPGRGTAVTIY
LPALEEAQLDRPASRRHDA